UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                ----------------

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

        Date of Report (Date of earliest event reported): April 16, 2004

                               CHIRAL QUEST, INC.
               (Exact Name of Registrant as Specified in Charter)

        Minnesota                  33-13058-C                    58-1486040
(State or Other Jurisdiction       (Commission                  (IRS Employer
     of Incorporation)             File Number)              Identification No.)

    Princeton Corporate Plaza
     7 Deer Park Drive, Suite E                                      08852
        Monmouth Junction, NJ                                      (Zip Code)
(Address of Principal Executive Offices)

        Registrant's telephone number, including area code: 732-274-0399

          (Former Name or Former Address, if Changed Since Last Report)




ITEM 5. OTHER EVENTS AND REQUIRED FD DISCLOSURE.

      On April 16, 2004,  the Company  announced that Alan D. Roth,  Ph.D.,  the
Company's  President,  Chief  Executive  Officer  and Chief  Financial  Officer,
recently  resigned  from  those  positions.  Dr.  Roth  also  resigned  from the
Company's  board of  directors.  Dr.  Roth will  continue  to be employed by the
Company  until June 30, 2004,  or such earlier date as Dr. Roth  determines,  in
order to assist the Company as it transitions to a new chief executive  officer.
During this transition  period, Dr. Roth will continue to receive his annualized
base salary of $240,000.  In  connection  with his  separation,  the Company has
agreed to pay Dr. Roth a severance  fee of  $375,000,  less the amount of salary
paid to him during the  remaining  period of his  employment.  Dr. Roth has also
agreed to terminate all of his outstanding stock options.

      The Company has immediately  begun  searching for Dr. Roth's  replacement.
Ronald Brandt,  the Company's  current Vice  President of Business  Development,
will serve as the Company's  interim chief  executive  officer until the Company
has found Dr. Roth's successor.  Additionally, Yaping Hong has been appointed to
serve as the Company's  interim chief operating  officer and Brian Lenz has been
appointed  interim chief financial  officer.  Mr. Hong has been with the Company
since June 2003  serving as its Director of Process  Research  and  Development.
Brian Lenz has served as the Company's  controller  since joining the Company in
October 2003 and as its secretary since January 2004.

      A copy of the  Separation  Agreement  between  Dr. Roth and the Company is
attached hereto as Exhibit 10.1. The Registrant's  press release dated April 16,
2004,  which is attached to this Current  Report on Form 8-K as Exhibit 99.1, is
incorporated by reference herein.

ITEM 7. FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

      (c)   Exhibits

      10.1  Separation Agreement dated effective as of April 2, 2004 between Dr.
            Alan Roth and the Company.

      99.1  Company's press release dated April 16, 2004.

                                   SIGNATURES

      Pursuant to the  requirements  of the Securities and Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                        CHIRAL QUEST, INC.

Date:  April 19, 2004                   By: /s/ Brian Lenz
                                           -------------------------------------
                                           Brian Lenz
                                           Interim Chief Financial Officer


                                       7


                                  EXHIBIT INDEX

10.1  Separation  Agreement dated effective as of April 2, 2004 between Dr. Alan
      Roth and the Company.

99.1  Company's press release dated April 16, 2004.