Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
BIENAIME JEAN JACQUES
  2. Issuer Name and Ticker or Trading Symbol
BIOMARIN PHARMACEUTICAL INC [BMRN]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Executive Officer
(Last)
(First)
(Middle)
C/O BIOMARIN PHARMACEUTICAL INC., 770 LINDARO ST.
3. Date of Earliest Transaction (Month/Day/Year)
12/24/2014
(Street)

SAN RAFAEL, CA 94901
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/24/2014(1) 12/24/2014 M   3,000 A $ 12.99 46,195 I Shares held by Bienaime Family Trust (2)
Common Stock 12/24/2014(1) 12/24/2014 S   3,000 D $ 88.731 (3) 43,195 I Shares held by Bienaime Family Trust (2)
Common Stock 12/24/2014(1) 12/24/2014 S   2,000 D $ 88.731 (3) 227,157 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy Common Stock) $ 12.99 12/24/2014(1) 12/24/2014 M     3,000 11/11/2006(4) 05/10/2016 Common Stock 3,000 $ 0 64,500 (5) I Shares Held by Bienaime Family Trust (2)
Stock Option (right to buy Common Stock) $ 12.99             11/11/2006(4) 05/10/2016 Common Stock 10,000   10,000 I Held in irrevocable trust for Guillaume Bienaime (6)
Stock Option (right to buy Common Stock) $ 12.99             11/11/2006(4) 05/10/2016 Common Stock 10,000   10,000 I Held in irrevocable trust for Pierre Bienaime (6)
Stock Option (right to buy Common Stock) $ 12.99             11/11/2006(4) 05/10/2016 Common Stock 10,000   10,000 I Held in irrevocable trust for Paul Bienaime (6)
Stock Option (right to buy Common Stock) $ 12.99             11/11/2006(4) 05/10/2016 Common Stock 10,000   10,000 I Held in irrevocable trust for Marc Bienaime (6)
Stock Option (right to buy Common Stock) $ 12.99             11/11/2006(4) 05/10/2016 Common Stock 20,000   20,000 I Held in irrevocable trust for Aurelie Mitsuki Bienaime & Anais Kimiko Bienaime (6)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
BIENAIME JEAN JACQUES
C/O BIOMARIN PHARMACEUTICAL INC.
770 LINDARO ST.
SAN RAFAEL, CA 94901
  X     Chief Executive Officer  

Signatures

 /s/ Laura Randall Woodhead, Attorney-in-Fact   12/29/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Trade made pursuant to a 10b5-1 plan executed November 6, 2014
(2) The reporting person an his spouse act as trustees for the Bienaime Family Trust
(3) The price in column 4 is an average weighted price. The price actually received ranged from $87.00 to $89.41. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range.
(4) Original option grant vests 6/48ths on November 11, 2006, and 1/48th on the 11th of every month thereafter.
(5) Reflects the number of stock options outstanding after the transaction from this specific stock option grant.
(6) The reporting person's spouse is the trustee of each child's trust.

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