================================================================================


                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 8-K/A

                               AMENDMENT NO. 1 TO
                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): August 21, 2002

                          BioMarin Pharmaceutical Inc.
               (Exact name of registrant as specified in its charter)


          Delaware                     000-26727                 68-0397820
(State or other jurisdiction of       (Commission              (IRS Employer
 incorporation or organization)       File Number)           Identification No.)


371 Bel Marin Keys Boulevard, Suite 210, Novato, California              94949
(Address of principal executive offices)                              (Zip Code)


Registrant's telephone number, including area code:               (415) 884-6700


                                    Not Applicable
           -------------------------------------------------------------
           (Former name or former address, if changed since last report)
================================================================================




BioMarin  Pharmaceutical  Inc.  (the  "Registrant")  hereby amends Item 7 of its
Current  Report on Form 8-K as filed with the  Commission  on August 26, 2002 to
include the financial  statements and pro forma financial  information set forth
below which was omitted from the previous  filing  pursuant to Items 7(a)(4) and
7(b)(2).

Item 7.  Financial Statements, Pro Forma Financial Statements and Exhibits.

         (a)   Financial Statements of Business Acquired.

               The  audited  financial   statements  of  Glyko  Biomedical  Ltd.
               ("Glyko") as of December  31, 2001 are filed  herewith as Exhibit
               99.2 to this Report.  Such financial  statements  were audited by
               Arthur Andersen LLP. After reasonable efforts, the Registrant has
               not been able to obtain the consent of Arthur Andersen LLP to the
               incorporation by reference of its audit report dated February 21,
               2002.  Therefore,  in reliance on Rule 437a promulgated under the
               Securities Act of 1933, as amended (the  "Securities  Act"),  the
               Registrant  has  dispensed  with  the  requirement  to  file  the
               reissued  report of Arthur  Andersen  LLP with  respect  to these
               financial statements.



               The unaudited financial statements of Glyko as of and for the six
               months ended June 30, 2002 are filed  herewith as Exhibit 99.3 to
               this Report.

         (b)   Pro Forma Financial Information.

               The  required   unaudited   pro  forma   consolidated   financial
               statements of the  Registrant  are filed herewith as Exhibit 99.4
               to this Report.

         (c)   Exhibits.

               2.1  Acquisition Agreement for a Plan of Arrangement, dated as of
                    February  6,  2002,  among  BioMarin   Pharmaceutical  Inc.,
                    BioMarin   Acquisition  (Nova  Scotia)  Company  and  Glyko
                    Biomedical  Ltd.,  previously  filed  on  April  1,  2002 as
                    Exhibit  2.5  to  the  Registrant's   Form  10-K,  which  is
                    incorporated herein by reference.

               2.2  Amending Agreement, dated as of May 16, 2002, among BioMarin
                    Pharmaceutical  Inc.,  BioMarin  Acquisition  (Nova  Scotia)
                    Company  and  Glyko  Biomedical  Ltd.,  previously  filed on
                    August 26, 2002 as Exhibit 2.2 to the Registrant's Form 8-K,
                    which is incorporated herein by reference.

               23.1 Statement Regarding Consent of Arthur Andersen LLP.

               99.1 Press  Release of the  Registrant  dated  August  22,  2002,
                    previously  filed on August 26, 2002 as Exhibit  99.1 to the
                    Registrant's  Form  8-K,  which is  incorporated  herein  by
                    reference.

               99.2 The audited financial statements of Glyko Biomedical Ltd. as
                    of and for the year ended December 31, 2001.

               99.3 The unaudited financial  statements of Glyko Biomedical Ltd.
                    as of and for the six month period ended June 30, 2002.

               99.4 The unaudited pro forma consolidated financial statements of
                    BioMarin  Pharmaceutical  Inc.  as of and for the six  month
                    period  ended June 30, 2002 and for the year ended  December
                    31, 2001.





                                    SIGNATURE

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                  BioMarin Pharmaceutical Inc.,
                                  a Delaware corporation


Date: October 18, 2002            By: /s/
                                      -----------------------------
                                        Louis Drapeau
                                        Chief Financial Officer, Vice President,
                                        Finance and Secretary



                                  EXHIBIT INDEX

Exhibit No.                Description

2.1                 Acquisition Agreement for a Plan of Arrangement, dated as of
                    February 6, 2002, by and among BioMarin Pharmaceutical Inc.,
                    BioMarin   Acquisition  (Nova  Scotia)  Company  and  Glyko
                    Biomedical  Ltd.,  previously  filed  on  April  1,  2002 as
                    Exhibit  2.5  to  the  Registrant's   Form  10-K,  which  is
                    incorporated herein by reference.

2.2                 Amending  Agreement,  dated as of May 16, 2002, by and among
                    BioMarin  Pharmaceutical  Inc.,  BioMarin  Acquisition (Nova
                    Scotia) Company and Glyko Biomedical Ltd.,  previously filed
                    on August 26, 2002 as Exhibit 2.2 to the  Registrant's  Form
                    8-K, which is incorporated herein by reference.

23.1                Statement Regarding Consent of Arthur Andersen LLP.

99.1                Press  Release of the  Registrant  dated  August  22,  2002,
                    previously  filed on August 26, 2002 as Exhibit  99.1 to the
                    Registrant's  Form  8-K,  which is  incorporated  herein  by
                    reference.

99.2                The audited financial statements of Glyko Biomedical Ltd. as
                    of and for the year ended December 31, 2001.

99.3                The unaudited financial  statements of Glyko Biomedical Ltd.
                    as of and for the six month period ended June 30, 2002.

99.4                The unaudited pro forma consolidated financial statements of
                    BioMarin  Pharmaceutical  Inc.  as of and for the six  month
                    period  ended June 30, 2002 and for the year ended  December
                    31, 2001.