MELBOURNE, Australia and INDIANAPOLIS, Feb. 27, 2026 (GLOBE NEWSWIRE) -- Telix Pharmaceuticals Limited (ASX: TLX, NASDAQ: TLX, “Telix”) today announces a research collaboration with University Hospital Essen on the PROMISE-PET registry1, defining the potential prognostic value of PSMA-PET2 imaging through artificial intelligence (AI).
PROMISE (PROstate cancer Molecular Imaging Standardized Evaluation)-PET is a multi-center, prospective, observational, non-interventional registry study designed to enable research assessing the prognostic value of PSMA-PET and comparing it with established clinical risk scores in early and late stages of disease. The registry has been collecting and analyzing patient data since 2018 and, to date, PET readings from more than 15,000 patients across over 50 institutions globally have been standardized using the PROMISE framework, with PSMA-PET and PROMISE confirmed as a novel prognostic biomarker for prostate cancer using both internal and external validation cohorts3.
The aim of this new collaboration with Telix is to develop and validate AI-based prediction models for survival, leveraging gallium-68 (68Ga)-PSMA-11-PET imaging data, using the automated machine learning (“AutoML”) engine that powers Telix’s AI platform4, and comparing performance with established clinically prognostic nomograms. PSMA-PET imaging represents a significant advance in prostate cancer management and is now considered standard of care, offering greater accuracy than conventional imaging (computed tomography and bone scans) after initial diagnosis and for detecting recurrence5. However, there remains an opportunity to better understand whether PSMA-PET imaging data can be correlated to patient outcomes.
Wolfgang Fendler, MD, Professor, Department of Nuclear Medicine, University Hospital Essen, commented, “We are pleased to welcome Telix – a leading global innovator in radiopharma – to the PROMISE-PET registry to support us in this important research in prostate cancer. Telix’s AI platform has the potential to build on existing results and leverage one of the world’s largest PSMA-PET datasets to support improved risk stratification and inform future guideline recommendations and clinical decision making.”
Simon Wail, Director of AI Research, Telix, added, “Joining the PROMISE-PET registry is an exciting moment for Telix. Working together with leading investigators and having access to global, longitudinal, standardized PSMA-PET data will enable us to build, test and validate clinically relevant prognostic models that we believe will help clinicians in their treatment and management of patients with prostate cancer.”
For further information on the PROMISE-PET registry, visit: https://www.promise-pet.org
About Telix Pharmaceuticals Limited
Telix is a biopharmaceutical company focused on the development and commercialization of therapeutic and diagnostic radiopharmaceuticals and associated medical technologies. Telix is headquartered in Melbourne, Australia, with international operations in the United States, United Kingdom, Brazil, Canada, Europe (Belgium and Switzerland), and Japan. Telix is developing a portfolio of clinical and commercial stage products that aims to address significant unmet medical needs in oncology and rare diseases. Telix is listed on the Australian Securities Exchange (ASX: TLX) and the Nasdaq Global Select Market (NASDAQ: TLX).
Illuccix® (kit for the preparation of gallium-68 (68Ga) gozetotide injection), Telix’s first generation PSMA-PET imaging agent, has been approved in multiple markets globally. Gozellix® (kit for the preparation of gallium-68 (68Ga) gozetotide injection) has been approved by the U.S. FDA6.
Visit www.telixpharma.com for further information about Telix, including details of the latest share price, ASX and U.S. Securities and Exchange Commission (SEC) filings, investor and analyst presentations, news releases, event details and other publications that may be of interest. You can also follow Telix on LinkedIn, X and Facebook
| Telix Investor Relations (Global) Ms. Kyahn Williamson SVP Investor Relations and Corporate Communications kyahn.williamson@telixpharma.com | Telix Investor Relations (Australia) Ms. Charlene Jaw Associate Director Investor Relations charlene.jaw@telixpharma.com | Telix Investor Relations (U.S.) Ms. Annie Kasparian Director Investor Relations and Corporate Communications annie.kasparian@telixpharma.com | ||
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1 ClinicalTrials.gov ID: NCT06320223.
2 Imaging of prostate-specific membrane antigen with positron emission tomography.
3 Eiber et al. J Nucl Med. 2018 (PROMISE V1); Seifert et al. European Urology. 2023 (PROMISE V2).
4 Telix ASX disclosure April 27, 2023.
5 EAU Guidelines. Edn. presented at the EAU Annual Congress Madrid 2025. ISBN 978-94-92671-29-5; Fendler et al. EJNMMI. 2023.
6 Telix ASX disclosure 21 March 2025.
