UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 
FORM 15
 
CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER
SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR
SUSPENSION OF DUTY TO FILE REPORTS UNDER
SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934.
 
Commission File Number: 000-20931
 
VENTANA MEDICAL SYSTEMS, INC.
(Exact name of registrant as specified in its charter)
 
 
1910 East Innovation Park Drive
Tucson, Arizona 85755
(520) 887-2155
(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)
 
 
Common Stock, $0.001 Par Value
Preferred Share Purchase Rights
(Title of each class of securities covered by this Form)
 
 
None
(Titles of all other classes of securities for which a duty to file reports under section 13(a) or 15(d) remains)
 
     Please place an X in the box(es) to designate the appropriate rule provision(s) relied upon to terminate or suspend the duty to file reports:

Rule 12g-4(a)(1)(i)
x
  
Rule 12h-3(b)(1)(i)
x
Rule 12g-4(a)(1)(ii)
o
  
Rule 12h-3(b)(1)(ii)
o
Rule 12g-4(a)(2)(i)
o
  
Rule 12h-3(b)(2)(i)
o
Rule 12g-4(a)(2)(ii)
o
  
Rule 12h-3(b)(2)(ii)
o
     
Rule 15d-6
o
 
     Approximate number of holders of record as of the certification or notice date: 1

Pursuant to the requirements of the Securities Exchange Act of 1934, Ventana Medical Systems, Inc. has caused this certification/notice to be signed on its behalf by the undersigned duly authorized person.

    VENTANA MEDICAL SYSTEMS, INC.   
           
           
Date: February 19, 2008
  
By:
/s/ Lawrence L. Mehren   
     
Lawrence L. Mehren 
  
     
Senior Vice President & Chief Financial Officer