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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM N-CSR

                   CERTIFIED SHAREHOLDER REPORT OF REGISTERED
                        MANAGEMENT INVESTMENT COMPANIES



		Investment Company Act file number 811-21409

                    Pioneer Municipal High Income Advantage Trust
               (Exact name of registrant as specified in charter)


                       60 State Street, Boston, MA 02109
              (Address of principal executive offices) (ZIP code)


            Terrence J. Cullen, Pioneer Investment Management, Inc.,
                       60 State Street, Boston, MA 02109
                    (Name and address of agent for service)


Registrant's telephone number, including area code:  (617) 742-7825


Date of fiscal year end:  March 31


Date of reporting period:  April 1, 2012 through September 30, 2012


Form N-CSR is to be used by management investment companies to file reports with
the Commission not later than 10 days after the transmission to stockholders of
any report that is required to be transmitted to stockholders under Rule 30e-1
under the Investment Company Act of 1940 (17 CFR 270.30e-1).  The Commission may
use the information provided on Form N-CSR in its regulatory, disclosure review,
inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-CSR,
and the Commission will make this information public. A registrant is not
required to respond to the collection of information contained in Form N-CSR
unless the Form displays a currently valid Office of Management and Budget
("OMB") control number. Please direct comments concerning the accuracy of the
information collection burden estimate and any suggestions for reducing the
burden to Secretary, Securities and Exchange Commission, 450 Fifth Street, NW,
Washington, DC 20549-0609.  The OMB has reviewed this collection of information
under the clearance requirements of 44 U.S.C. ss. 3507.


ITEM 1. REPORTS TO SHAREOWNERS.


                        Pioneer Municipal High
                        Income Advantage Trust

--------------------------------------------------------------------------------
                        Semiannual Report | September 30, 2012
--------------------------------------------------------------------------------

                        Ticker Symbol:   MAV

                        [LOGO] PIONEER
                               Investments(R)


                      visit us: us.pioneerinvestments.com


Table of Contents


                                                                          
Letter to Shareowners                                                         2

Portfolio Management Discussion                                               4

Portfolio Summary                                                            10

Prices and Distributions                                                     11

Performance Update                                                           12

Schedule of Investments                                                      13

Financial Statements                                                         25

Notes to Financial Statements                                                30

Trustees, Officers and Service Providers                                     39


   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 1


President's Letter

Dear Shareowner,

The U.S. stock market rallied sharply through the third quarter of 2012 amid a
sluggish, but nonetheless growing, U.S. economy. We have been cautiously
optimistic about the U.S. from the start of the year, and the economic data
continue to be encouraging. The housing and auto sectors are benefitting from
record-low interest rates. The climate for consumer and business credit has
improved, and inflation appears to be subdued. While corporate profits slowed in
the third quarter, many U.S. companies continue to have strong balance sheets
and to pay attractive dividends* compared to fixed-income securities.

All of these factors contributed to gains for investors who owned riskier
assets, including equities and higher-yielding corporate bonds. Year to date
through September 30, 2012, the Standard & Poor's 500 Index returned 16.35%. In
fixed income, the Bank of America Merrill Lynch High Yield Master II Index was
up by 12.02% during the same period, while the Barclays Capital Aggregate Bond
Index gained 3.99%. Treasury bonds, by contrast, generated a comparatively
sluggish return of 1.70%, as measured by the Barclays Capital Intermediate
Treasuries Index.

Despite this generally positive picture during the first nine months of 2012,
investors face powerful macroeconomic challenges in the months ahead. These
include the threat of a so-called "fiscal cliff" in the U.S. budget process
after the November elections, the European sovereign-debt crisis, and slowing
growth in both Europe and China. Investors can continue to count on market
volatility tied to these factors, although we remain optimistic that the
underlying economic trends are moving in the right direction.

At Pioneer, we have long advocated the benefits of staying diversified** and
investing for the long term. And while diversification alone does not assure a
profit or protect against loss in a declining market, we believe in actively
seeking out opportunities in undervalued securities and sectors around the
globe. Our advice, as always, is to work closely with a trusted financial
advisor to discuss your goals and work together to develop an investment
strategy that meets your individual needs. There is no single best strategy that
works for every investor.

*   Dividends are not guaranteed.
**  Diversification does not assure a profit or protect against loss in a
    declining market.

2 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Pioneer's investment professionals focus on finding good opportunities in both
equity and bond markets using the same disciplined investment approach we have
used since 1928. Our strategy is to identify undervalued individual securities
with the greatest potential for success, carefully weighing risk against reward.
Our teams of investment professionals continually monitor and analyze the
relative valuations of different sectors and securities globally to help build
portfolios that we believe can help you achieve your investment goals.

We invite you to learn more about Pioneer and our time-tested approach to
investing by consulting with your financial advisor or visiting us online at
us.pioneerinvestments.com. We greatly appreciate your trust in us, and we thank
you for investing with Pioneer.

Sincerely,

/s/ Daniel K. Kingsbury

Daniel K. Kingsbury
President and CEO
Pioneer Investment Management USA, Inc.

Any information in this shareowner report regarding market or economic trends or
the factors influencing the Trust's historical or future performance are
statements of opinion as of the date of this report. These statements should not
be relied upon for any other purposes. Past performance is no guarantee of
future results, and there is no guarantee that market forecasts discussed will
be realized.

   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 3


Portfolio Management Discussion | 9/30/12

Tax-advantaged municipal securities produced healthy returns during the six
months ended September 30, 2012, as both traditional and non-traditional
investors were drawn by attractive values in the municipal market when compared
to the taxable market. In the following interview, David Eurkus discusses the
factors that influenced the performance of Pioneer Municipal High Income
Advantage Trust over the six-month period. Mr. Eurkus, senior vice president and
portfolio manager at Pioneer, is responsible for the daily management of the
Trust.

Q   How did Pioneer Municipal High Income Advantage Trust perform during the
    six-month period ended September 30, 2012?

A   Pioneer Municipal High Income Advantage Trust produced a total return of
    9.77% at net asset value, and 12.69% at market price, during the six-month
    period ended September 30, 2012. During the same six-month period, the
    Trust's benchmarks, the Barclays Capital Municipal Bond Index and the
    Barclays Capital High Yield Municipal Bond Index, returned 4.24% and 8.06%,
    respectively. The Barclays Capital Municipal Bond Index is designed to track
    the performance of investment-grade municipal bonds, while the Barclays
    Capital High Yield Municipal Bond Index is designed to track the performance
    of lower-rated municipal bonds. During the same six-month period, the
    average return (at market price) of the 12 closed end funds in Lipper's High
    Yield Municipal Debt Closed End Funds category (which may or may not be
    leveraged) was 14.10%.

    The shares of the Trust were selling at a 17.7% premium to net asset value
    at the end of the period.

    Unlike the Trust, the two Barclays Capital municipal indices do not use
    leverage. While the use of leverage can increase investment opportunity, it
    also can increase investment risk.

    On September 30, 2012, the standardized 30-day SEC yield on the Trust's
    shares was 3.84%.

Q   How would you describe the investment environment during the six-month
    period ended September 30, 2012?

A   The six-month period ended September 30, 2012, was a favorable one for
    municipal securities in general, with new money flowing into the municipal
    market. Inflows came from traditional investors seeking tax advantages as
    well as from institutional investors, such as banks and insurance companies,
    who were attracted by the competitive yields available from municipal

4 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


    securities compared with taxable investments. Both investment-grade and
    higher-yielding, below-investment-grade municipal securities produced more
    income, on an after-tax basis, than taxable securities of comparable quality
    and with similar maturities. As demand for municipal securities rose while
    supply remained limited, municipal bond prices increased and interest rates
    declined, delivering total returns that often were superior to those
    available in the taxable market during the six-month period. Moreover,
    municipal revenue bonds continued to be perceived as a relatively safe place
    for investors' money.

Q   How was the Trust's portfolio positioned over the six-month period ended
    September 30, 2012, and how did the positioning affect the Trust's
    performance?

A   During the six-month period, we maintained our traditional emphasis on
    project revenue bonds within the Trust's portfolio. Project revenue bonds
    are secured by dedicated revenue streams from specific projects, such as
    hospitals or other health care institutions, or airport revenues. We focus
    the Trust's investments in these types of securities because of the
    reliability of their funding sources as compared with general obligation
    bonds, which do not require a dedicated revenue stream and can be more
    affected by credit rating downgrades or the general fiscal problems of a
    municipality or agency.

    At the end of the period on September 30, 2012, health care continued to
    represent the largest allocation in the Trust's total investment portfolio,
    at 20.7% of invested assets, followed by insurance bonds (16.3% of invested
    assets) and tobacco revenue bonds (13.7% of invested assets). Other project
    revenue allocations in the Trust's portfolio included those in the airport
    and airport facilities, education, housing, pollution control, and water and
    sewer sectors.

    As of September 30, 2012, 47.3% of the Trust's total investment portfolio
    was invested in securities with investment-grade credit ratings, while 52.7%
    of the Trust's total investment portfolio was held in high-yield securities.

    We kept the Trust fully invested during the six-month period and maintained
    a duration positioning that was longer than that of the benchmarks. The
    longer-duration positioning helped the Trust to capture fully the benefits
    of the falling interest rates and the resulting increases in bond prices
    during the six-month period.

   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 5


Q   Did any particular types of investments have notable effects on the Trust's
    performance during the six-month period ended September 30, 2012?

A   In addition to benefiting from the portfolio's longer-duration positioning,
    the Trust's performance during the six-month period was aided by established
    positions with adequate call protection that had much higher yields than
    those currently available. Call protection limits the issuers' ability to
    call back their debt in order to refinance into lower-yielding substitutes.

    The Trust's performance also benefited from strong security selection
    results from investments in both high-yield and investment-grade securities
    across a wide spectrum of sectors, with positions in the hospital and health
    care, transportation and education groups performing particularly well
    during the six-month period.

    Our investment process for the Trust relies heavily on basic, fundamental
    research and the analysis of individual securities as well as the
    reliability of those securities' funding sources. We believe the success of
    the investment process can especially be seen in the Trust's performance
    results from the hospital and health care and industrial revenue groups.
    Notable examples of strong-performing individual securities in the Trust's
    portfolio during the period include: Temple University (Philadelphia)
    Hospital bonds; State of Pennsylvania Industrial Revenue bonds for U.S.
    Gypsum; and State of California general obligation bonds.

    In transportation, a noteworthy contributor to the Trust's performance
    during the six-month period was an airport facility security backed by
    revenues from American Airlines. That particular investment had fallen in
    value prior to the start of the period after AMR, the parent company of the
    airline, filed for bankruptcy protection in November 2011. The bond price
    appreciated during the six-month period ended September 30, 2012, as
    investors recognized the secured nature of the revenue stream dedicated to
    the security.

    Despite strong overall performance, the Trust did own a couple of
    underperforming securities during the period. Specifically, the Trust's
    holdings of St. Louis Industrial Development Authority (hotel-related
    revenue bonds), the performance of which suffered due to a restructuring of
    the debt, and Non-Profit Preferred Funding Trust (variable-rate municipal
    pool), whose underperformance was related to low distributions relative to
    other securities in the Trust's portfolio, generated negative returns during
    the six-month period.

6 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Q   How did the level of leverage employed by the Trust change over the
    six-month period ended September 30, 2012?

A   At the end of the six-month period ended September 30, 2012, 32.1% of the
    Trust's total managed assets were financed by leverage, compared with 33.4%
    of the Trust's total managed assets financed by leverage at the start of the
    period on April 1, 2012. The decrease was due to fluctuations in the values
    of securities in which the Trust had invested.

Q   What is your investment outlook?

A   While the capital markets face a number of issues, we think there continue
    to be good values and attractive opportunities available in the municipal
    market--both in high-yield and investment-grade securities. In the current
    environment, we think credit research will remain essential for investment
    success. That is especially true when selecting project revenue bonds, which
    we emphasize in the Trust's investment strategy. We believe we will see in
    the future the continued need for financing of essential projects, and that
    need should provide quality investment opportunities for those who focus on
    fundamental research of the strengths and financial reliability of each
    proposed project.

    We certainly foresee many challenges ahead, including geopolitical issues in
    the Middle East, the continuing political debate in the U.S. over the
    country's national debt, levels of taxation, and discretionary spending
    policies, and litigation over public pension funds.

    We plan to stay focused on intensive, independent research when selecting
    securities for the Trust's portfolio, looking at the different sectors
    involved in public finance and examining which areas we believe are most
    likely to have secure revenues, and which services are considered to be most
    essential. We are watching carefully for new areas of investment
    opportunity, which may include financing for charter schools, seaport
    facility expansions, toll road construction and maintenance, and energy
    production. We also will seek to identify which regional or national
    projects are unlikely to receive further support from the U.S. government.

Please refer to the Schedule of Investments on pages 13-24 for a full listing of
Trust securities.

   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 7


Investments in high-yield or lower-rated securities are subject to
greater-than-average risk.

The Trust may invest in securities of issuers that are in default or that are in
bankruptcy.

A portion of income may be subject to state, federal, and/or alternative minimum
tax. Capital gains, if any, are subject to a capital gains tax.

When interest rates rise, the prices of fixed-income securities in the Trust
will generally fall. Conversely, when interest rates fall, the prices of
fixed-income securities in the Trust will generally rise.

By concentrating in municipal securities, the portfolio is more susceptible to
adverse economic, political or regulatory developments than is a portfolio that
invests more broadly.

Investments in the Trust are subject to possible loss due to the financial
failure of the issuers of the underlying securities and the issuers' inability
to meet their debt obligations.

The Trust currently uses leverage through the issuance of preferred shares.
Leverage creates significant risks, including the risk that the Trust's income
or capital appreciation will not be sufficient to cover the cost of leverage,
which may adversely affect the return for the holders of common shares. Since
February of 2008, regularly scheduled auctions for the Trust's preferred shares
have failed and preferred shareowners have not been able to sell their shares at
auction. The Board of Trustees of the Trust has considered, and continues to
consider, this issue.

The Trust is required to maintain certain regulatory and rating agency asset
coverage requirements in connection with its outstanding preferred shares. In
order to maintain required asset coverage levels, the Trust may be required to
alter the composition of its investment portfolio or take other actions, such as
redeeming preferred shares with the proceeds from portfolio transactions, at
what might be inopportune times in the market. Such actions could reduce the net
earnings or returns to holders of the Trust's common shares over time.

Risks of investing in the Trust are discussed in greater detail in the Trust's
original offering documents relating to its common shares and shareowner reports
issued from time to time.

These risks may increase share price volatility.

8 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Past performance is no guarantee of future results, and there is no guarantee
that market forecasts discussed will be realized.

Any information in this shareowner report regarding market or economic trends or
the factors influencing the Trust's historical or future performance are
statements of opinion as of the date of this report. These statements should not
be relied upon for any other purposes.

   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 9


Portfolio Summary | 9/30/12

Portfolio Diversification
--------------------------------------------------------------------------------
(As a percentage of total investment portfolio)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]



                                                                        
Health Revenue                                                             20.7%
Insured                                                                    16.2%
Tobacco Revenue                                                            13.7%
Facilities Revenue                                                         12.6%
Development Revenue                                                         9.4%
Other Revenue                                                               8.6%
Airport Revenue                                                             6.1%
Education Revenue                                                           4.5%
Pollution Control Revenue                                                   3.8%
Transportation Revenue                                                      2.4%
Water Revenue                                                               1.9%
Utilities Revenue                                                           0.1%


Portfolio Maturity
--------------------------------------------------------------------------------
(As a percentage of long-term holdings)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]



                                                                        
20+ years                                                                  67.4%
10-20 years                                                                28.9%
7-10 years                                                                  1.1%
5-7 years                                                                   0.8%
2-5 years                                                                   0.5%
0-2 year                                                                    1.3%


Quality  Distribution
--------------------------------------------------------------------------------
(As a percentage of total investment portfolio; based on Standard & Poor's
ratings)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]



                                                                        
AAA                                                                         3.0%
AA                                                                         17.8%
A                                                                           8.0%
BBB                                                                        18.5%
BB                                                                          7.6%
B                                                                           8.6%
CCC                                                                         2.1%
D                                                                           0.1%
Not Rated                                                                  34.3%


Bond ratings are ordered highest to lowest in portfolio. Based on Standard &
Poor's measures, AAA (highest possible rating) through BBB are considered
investment grade; BB or lower ratings are considered non-investment grade. Cash
equivalents and some bonds may not be rated.

The portfolio is actively managed and current holdings may be different.

10 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Prices and Distributions | 9/30/12

Share Prices and Distributions
--------------------------------------------------------------------------------

Market Value per Common Share
--------------------------------------------------------------------------------



--------------------------------------------------------------------------------
                                   9/30/12                  3/31/12
--------------------------------------------------------------------------------
                                                       
                                   $15.99                    $14.72
--------------------------------------------------------------------------------
Premium                             17.7%                     14.4%
--------------------------------------------------------------------------------


Net Asset Value per Common Share
--------------------------------------------------------------------------------



                                                      
--------------------------------------------------------------------------------
                                   9/30/12                  3/31/12
--------------------------------------------------------------------------------
                                    $13.59                   $12.87
--------------------------------------------------------------------------------


Distributions per Common Share
--------------------------------------------------------------------------------



--------------------------------------------------------------------------------
                              Net
                          Investment         Short-Term           Long-Term
                            Income          Capital Gains       Capital Gains
--------------------------------------------------------------------------------
                                                            
4/1/12-9/30/12              $0.57                $--                 $--
--------------------------------------------------------------------------------


10 Largest Holdings
--------------------------------------------------------------------------------
(As a percentage of long-term holdings)*



                                                                          
  1.  University of California, RIB, 13.177%, 5/15/32                           2.60%
-------------------------------------------------------------------------------------
  2.  North Texas Tollway Authority Revenue, 5.75%, 1/1/33                      2.41
-------------------------------------------------------------------------------------
  3.  Massachusetts Housing Finance Agency Revenue, 5.35%, 12/1/45              2.41
-------------------------------------------------------------------------------------
  4.  Massachusetts Development Finance Agency Revenue, 5.75%, 1/1/42           2.35
-------------------------------------------------------------------------------------
  5.  Lehman Municipal Trust Receipts General Obligations, 12.866%, 7/28/31     2.35
-------------------------------------------------------------------------------------
  6.  Houston Texas Airport System Special Facilities Revenue, 6.75%, 7/1/29    2.23
-------------------------------------------------------------------------------------
  7.  California County Tobacco Securitization Agency Revenue, 5.25%, 6/1/46    1.93
-------------------------------------------------------------------------------------
  8.  New Jersey Transportation Trust Fund Authority Revenue, 0.0%, 12/15/27    1.87
-------------------------------------------------------------------------------------
  9.  Tobacco Settlement Financing Corp., Revenue, 6.25%, 6/1/42                1.87
-------------------------------------------------------------------------------------
 10.  Non-Profit Preferred Funding Trust I, 6.75%, 9/15/37                      1.83
-------------------------------------------------------------------------------------


*   This list excludes temporary cash investments and derivative instruments.
    The portfolio is actively managed, and current holdings may be different.
    The holdings listed should not be considered recommendations to buy or sell
    any security listed.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 11


Performance Update | 9/30/12

Investment Returns
--------------------------------------------------------------------------------
The mountain chart on the right shows the change in market value, including
reinvestment of dividends and distributions, of a $10,000 investment made in
common shares of Pioneer Municipal High Income Advantage Trust, compared to that
of the Barclays Capital Municipal Bond Index and the Barclays Capital High Yield
Municipal Bond Index.



Average Annual Total Returns
(As of March 31, 2012)
--------------------------------------------------------------------------------
                             Net Asset       Market
Period                       Value (NAV)     Price
--------------------------------------------------------------------------------
                                       
Life-of-Class
(10/17/2003)                  7.33%           8.74%
5 Years                       6.31            9.59
1 Year                       16.77           18.00
--------------------------------------------------------------------------------


[THE FOLLOWING DATA WAS REPRESENTED AS A MOUNTAIN CHART IN THE PRINTED MATERIAL]

Value of $10,000 Investment



             Pioneer Municipal High   Barclays Capital       Barclays Capital High
             Income Advantage Trust   Municipal Bond Index   Yield Municipal Bond Index
                                                    
10/31/2003   $  10,000                $  10,000              $  10,000
9/30/2004    $   9,965                $  10,513              $  11,043
9/30/2005    $  11,335                $  10,939              $  12,231
9/30/2006    $  12,310                $  11,425              $  13,544
9/30/2007    $  13,392                $  11,779              $  13,932
9/30/2008    $   9,595                $  11,559              $  12,533
9/30/2009    $  12,443                $  13,275              $  13,104
9/30/2010    $  15,558                $  14,046              $  14,694
9/30/2011    $  16,720                $  14,592              $  15,308
9/30/2012    $  21,180                $  15,805              $  17,571


Call 1-800-225-6292 or visit us.pioneerinvestments.com for the most recent
month-end performance results. Current performance may be lower or higher than
the performance data quoted.

Performance data shown represents past performance. Past performance is no
guarantee of future results. Investment return and market price will fluctuate,
and your shares may trade below NAV due to such factors as interest rate changes
and the perceived credit quality of borrowers.

Total investment return does not reflect broker sales charges or commissions.
All performance is for common shares of the Trust.

Closed-end funds, unlike open-end funds, are not continuously offered. There is
a one-time public offering and, once issued, shares of closed-end funds are sold
in the open market through a stock exchange, and frequently trade at prices
lower than their NAV. NAV per common share is total assets less total
liabilities, which includes preferred shares, divided by the number of common
shares outstanding.

When NAV is lower than market price, dividends are assumed to be reinvested at
the greater of NAV or 95% of the market price. When NAV is higher, dividends are
assumed to be reinvested at prices obtained under the Trust's dividend
reinvestment plan.

The performance table and graph do not reflect the deduction of fees and taxes
that a shareowner would pay on Trust distributions or the sale of Trust shares.

Index comparison begins October 31, 2003. The Barclays Capital Municipal Bond
Index is a broad measure of the municipal bond market. The Barclays Capital High
Yield Municipal Bond Index totals over $26 billion in market value and maintains
over 1300 securities. Municipal bonds in this index have the following
requirements: maturities of one year or greater, sub investment grade (below Baa
or non-rated), fixed coupon rate, issue date later than 12/31/90, deal size over
$20 million, maturity size of at least $3 million. Index returns are calculated
monthly, assume reinvestment of dividends and, unlike Trust returns, do not
reflect any fees, expenses or sales charges. The indices do not employ leverage.
You cannot invest directly in the indices.

12 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Schedule of Investments | 9/30/12 (unaudited)


------------------------------------------------------------------------------------------------------------
Principal
Amount                 S&P/Moody's
USD ($)                Ratings                                                             Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                       TAX EXEMPT OBLIGATIONS -- 139.2% of Net Assets
                                       Alabama -- 1.6%
        2,500,000              B-/B2   Alabama Industrial Development Authority Solid
                                       Waste Disposal Revenue, 6.45%, 12/1/23              $       2,499,675
        2,500,000              NR/NR   Huntsville-Redstone Village Special Care
                                       Facilities
                                       Financing Authority, 5.5%, 1/1/43                           2,496,100
                                                                                           -----------------
                                                                                           $       4,995,775
------------------------------------------------------------------------------------------------------------
                                       Arizona -- 3.3%
        5,000,000              NR/NR   Casa Grande Industrial Development Authority
                                       Hospital Revenue, 7.625%, 12/1/29                   $       5,152,300
        1,487,000            NR/Baa3   Pima County Industrial Development Authority,
                                       6.75%, 7/1/31                                               1,489,840
        2,640,000              NR/NR   Pima County Industrial Development Authority,
                                       7.0%, 1/1/38                                                2,733,192
        1,000,000              NR/NR   San Luis Facility Development Corp.,
                                       7.25%, 5/1/27                                                 962,550
                                                                                           -----------------
                                                                                           $      10,337,882
------------------------------------------------------------------------------------------------------------
                                       California -- 19.1%
       11,990,000             CCC/NR   California County Tobacco Securitization Agency
                                       Revenue, 5.25%, 6/1/46                              $       8,659,538
        1,450,000              NR/NR   California Enterprise Development Authority
                                       Recovery Zone Facility Revenue, 8.5%, 4/1/31                1,681,463
        2,425,000              A-/A1   California State General Obligation Various
                                       Purpose, 5.75%, 4/1/31                                      2,882,840
        4,000,000              BB/NR   California Statewide Communities Development
                                       Authority, 7.25%, 10/1/38 (144A)                            4,284,440
          757,342(a)           NR/NR   California Statewide Communities Development
                                       Authority Environmental Facilities Revenue,
                                       9.0%, 12/1/38                                                   6,733
        2,680,000(b)         AA+/Aaa   Golden State Tobacco Securitization Corp.,
                                       6.75%, 6/1/39                                               2,797,973
        2,500,000             NR/Ba1   Hesperia Public Financing Authority Tax
                                       Allocation,
                                       5.5%, 9/1/27                                                2,389,600
        8,575,000(c)          AA-/NR   Lehman Municipal Trust Receipts General
                                       Obligation, 12.866%, 7/28/31                               10,569,202
        3,140,000             AA-/WR   Lehman Municipal Trust Receipts Revenue, RIB,
                                       12.959%, 9/20/28 (144A)                                     3,998,602
        1,500,000              A-/NR   Madera Irrigation Financing Authority Water
                                       Revenue, 6.25%, 1/1/31                                      1,686,555
        1,500,000              A-/NR   Madera Irrigation Financing Authority Water
                                       Revenue, 6.5%, 1/1/40                                       1,697,760
        2,500,000              A-/A2   San Jose California Airport Revenue, 5.0%, 3/1/37           2,625,225
        7,000,000            B-/Caa1   Tobacco Securitization Authority of Northern
                                       California Revenue, 5.375%, 6/1/38                          5,691,000
       10,500,000             AA-/NR   University of California, RIB, 13.177%, 5/15/32            11,700,570
                                                                                           -----------------
                                                                                           $      60,671,501
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 13


Schedule of Investments | 9/30/12 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                       Colorado -- 0.3%
$       1,000,000              NR/NR   Kremmling Memorial Hospital District Certificate
                                       of Participation, 7.125%, 12/1/45                   $       1,118,750
------------------------------------------------------------------------------------------------------------
                                       Connecticut -- 2.8%
        7,750,000           BBB/Baa1   Connecticut State Development Authority Revenue,
                                       5.75%, 11/1/37                                      $       7,758,215
        1,000,000              NR/NR   Hamden Connecticut Facility Revenue,
                                       7.75%, 1/1/43                                               1,094,240
                                                                                           -----------------
                                                                                           $       8,852,455
------------------------------------------------------------------------------------------------------------
                                       District of Columbia -- 3.1%
        2,700,000           BBB/Baa1   District of Columbia Tobacco Settlement
                                       Financing Corp., 6.5%, 5/15/33                      $       3,058,911
        6,825,000           BBB/Baa1   District of Columbia Tobacco Settlement
                                       Financing Corp., 6.75%, 5/15/40                             6,960,886
                                                                                           -----------------
                                                                                           $      10,019,797
------------------------------------------------------------------------------------------------------------
                                       Florida -- 4.7%
        1,500,000              NR/NR   Alachua County Health Facilities Authority
                                       Revenue, 8.125%, 11/15/41                           $       1,735,140
        1,500,000              NR/NR   Alachua County Health Facilities Authority
                                       Revenue, 8.125%, 11/15/46                                   1,729,410
          500,000             NR/Ba3   Capital Trust Agency Revenue Bonds,
                                       7.75%, 1/1/41                                                 557,120
        1,000,000              NR/NR   Florida Development Finance Corp., Educational
                                       Facilities Revenue, 6.0%, 9/15/40                           1,073,840
        2,000,000              NR/NR   Florida Development Finance Corp., Educational
                                       Facilities Revenue, 7.625%, 6/15/41                         2,320,560
        1,000,000              NR/NR   Florida Development Finance Corp., Educational
                                       Facilities Revenue, 7.75%, 6/15/42                          1,133,100
        1,980,000              NR/NR   Hillsborough County Industrial Development
                                       Authority, 6.75%, 7/1/29                                    1,981,564
        1,000,000(b)           NR/WR   Hillsborough County Industrial Development
                                       Authority Revenue, 8.0%, 8/15/32                            1,426,900
        2,500,000              A-/A2   Miami-Dade County Florida Aviation Revenue,
                                       5.5%, 10/1/41                                               2,856,750
                                                                                           -----------------
                                                                                           $      14,814,384
------------------------------------------------------------------------------------------------------------
                                       Georgia -- 4.3%
        5,210,000             AA-/WR   Atlanta Georgia Water and Wastewater Revenue,
                                       RIB, 12.959%, 1/30/13 (144A)                        $       5,825,718
        1,000,000            CCC+/NR   Clayton County Development Authority Revenue,
                                       9.0%, 6/1/35                                                1,121,500
          900,000              NR/NR   DeKalb County Georgia Hospital Authority Revenue,
                                       6.0%, 9/1/30                                                1,051,803
          750,000              NR/NR   DeKalb County Georgia Hospital Authority Revenue,
                                       6.125%, 9/1/40                                                870,007
        3,360,000              NR/NR   Fulton County Residential Care Facilities for the
                                       Elderly Authority, 7.0%, 7/1/29                             3,026,554


The accompanying notes are an integral part of these financial statements.

14 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12




------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                       Georgia -- (continued)
     $ 1,650,000               NR/NR   Savannah Georgia Economic Development
                                       Authority Revenue, 7.4%, 1/1/34                     $       1,688,379
                                                                                           -----------------
                                                                                           $      13,583,961
------------------------------------------------------------------------------------------------------------
                                       Guam -- 1.8%
       1,000,000                B/NR   Guam Government of Department Education
                                       Certificates of Participation, 6.625%, 12/1/30      $       1,092,610
       4,400,000(b)           AA+/B2   Northern Mariana Islands, 6.75%, 10/1/33                    4,668,224
                                                                                           -----------------
                                                                                           $       5,760,834
------------------------------------------------------------------------------------------------------------
                                       Idaho -- 1.1%
       2,000,000           BBB+/Baa1   Power County Industrial Development Corp.
                                       Revenue, 6.45%, 8/1/32                              $       2,003,460
       1,500,000           BBB+/Baa1   Power County Pollution Control Revenue,
                                       5.625%, 10/1/14                                             1,501,395
                                                                                           -----------------
                                                                                           $       3,504,855
------------------------------------------------------------------------------------------------------------
                                       Illinois -- 6.6%
       1,000,000             NR/Baa2   City of Country Club Hills General Obligation,
                                       5.0%, 12/1/31                                       $       1,034,840
       1,450,000               A+/A1   Illinois Finance Authority Revenue, 5.5%, 4/1/39            1,583,965
       1,605,000             AA-/Aa3   Illinois Finance Authority Revenue, 6.0%, 8/15/25           1,712,391
       1,000,000(a)            NR/NR   Illinois Finance Authority Revenue,
                                       6.0%, 11/15/27                                                302,510
         280,000             BBB+/NR   Illinois Finance Authority Revenue, 6.0%, 8/15/38             318,536
       2,000,000             AA+/Aa2   Illinois Finance Authority Revenue, 6.0%, 8/15/39           2,352,760
       2,500,000               NR/NR   Illinois Finance Authority Revenue,
                                       6.125%, 11/15/25                                            2,585,250
       6,000,000               NR/NR   Illinois Finance Authority Revenue,
                                       8.25%, 5/15/45                                              6,559,020
       2,500,000               NR/NR   Illinois Finance Authority Revenue,
                                       8.25%, 2/15/46                                              2,716,400
       2,270,000               NR/NR   Southwestern Illinois Development Authority
                                       Revenue, 5.625%, 11/1/26                                    1,942,530
                                                                                           -----------------
                                                                                           $      21,108,202
------------------------------------------------------------------------------------------------------------
                                       Indiana -- 0.9%
         250,000               NR/NR   City of Carmel Indiana Nursing Home Revenue,
                                       7.0%, 11/15/32                                      $         252,753
         750,000               NR/NR   City of Carmel Indiana Nursing Home Revenue,
                                       7.125%, 11/15/42                                              758,205
         500,000               NR/NR   City of Carmel Indiana Nursing Home Revenue,
                                       7.125%, 11/15/47                                              503,700
         250,000             NR/Baa3   East Chicago Indiana Exempt Facilities Revenue,
                                       7.0%, 1/1/14                                                  251,565
       1,805,000               NR/NR   Vincennes Industrial Economic Development
                                       Revenue, 6.25%, 1/1/24                                      1,105,905
                                                                                           -----------------
                                                                                           $       2,872,128
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 15


Schedule of Investments | 9/30/12 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                       Kansas -- 0.3%
     $ 1,000,000              NR/A2    Kansas Development Finance Authority Revenue,
                                       5.0%, 5/15/35                                       $       1,090,510
------------------------------------------------------------------------------------------------------------
                                       Kentucky -- 1.4%
       4,390,000              BB/NR    Kentucky Economic Development Finance
                                       Authority Hospital System Revenue,
                                       5.875%, 10/1/22                                     $       4,393,205
------------------------------------------------------------------------------------------------------------
                                       Louisiana -- 5.9%
       5,000,000          BBB-/Baa2    Jefferson Parish Hospital Service Revenue,
                                       6.375%, 7/1/41                                      $       5,837,550
       2,500,000          BBB-/Baa3    Louisiana Local Government Environmental
                                       Facilities & Community Development Authority
                                       Revenue, 6.75%, 11/1/32                                     2,817,450
       6,000,000            NR/Baa1    Louisiana Public Facilities Authority Revenue,
                                       5.5%, 5/15/47                                               6,323,940
         750,000            BBB-/NR    Opelousas Louisiana General Hospital Authority
                                       Revenue, 5.75%, 10/1/23                                       771,720
       2,915,000              A-/A3    Tobacco Settlement Financing Corp. Revenue,
                                       5.875%, 5/15/39                                             2,973,009
                                                                                           -----------------
                                                                                           $      18,723,669
------------------------------------------------------------------------------------------------------------
                                       Maine -- 0.6%
       1,500,000            NR/Baa3    Maine Health & Higher Educational Facilities
                                       Authority Revenue, 7.5%, 7/1/32                     $       1,874,475
------------------------------------------------------------------------------------------------------------
                                       Maryland -- 1.7%
         460,000              NR/NR    Maryland Health & Higher Educational Facilities
                                       Authority Revenue, 5.25%, 1/1/27                    $         450,473
       1,250,000              NR/NR    Maryland Health & Higher Educational Facilities
                                       Authority Revenue, 5.3%, 1/1/37                             1,168,738
       1,250,000            NR/Baa3    Maryland Health & Higher Educational Facilities
                                       Authority Revenue, 5.75%, 7/1/38                            1,360,662
       2,000,000              NR/NR    Maryland Health & Higher Educational Facilities
                                       Authority Revenue, 6.25%, 1/1/45                            2,312,160
                                                                                           -----------------
                                                                                           $       5,292,033
------------------------------------------------------------------------------------------------------------
                                       Massachusetts -- 9.5%
         675,000              BB/NR    Massachusetts Development Finance Agency
                                       Revenue, 5.25%, 10/1/18                             $         675,209
       8,000,000               A/WR    Massachusetts Development Finance Agency
                                       Revenue, 5.75%, 1/1/42                                     10,585,520
       1,845,000              NR/NR    Massachusetts Development Finance Agency
                                       Revenue, 7.1%, 7/1/32                                       1,845,683
       2,195,000          BBB-/Baa3    Massachusetts Health & Educational Facilities
                                       Authority Revenue, 5.375%, 7/15/28                          2,196,032
       2,000,000            AAA/Aaa    Massachusetts Health & Educational Facilities
                                       Authority Revenue, 5.5%, 7/1/32                             2,887,760
       1,000,000            NR/Baa2    Massachusetts Health & Educational Facilities
                                       Authority Revenue, 6.0%, 10/1/23                            1,001,220


The accompanying notes are an integral part of these financial statements.

16 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12




------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                      Massachusetts -- (continued)
     $ 3,420,000(a)           NR/NR   Massachusetts Health & Educational Facilities
                                      Authority Revenue, 6.5%, 1/15/38                     $          17,305
      10,760,000            AA-/Aa3   Massachusetts Housing Finance Agency Revenue,
                                      5.35%, 12/1/45                                              10,821,332
                                                                                           -----------------
                                                                                           $      30,030,061
------------------------------------------------------------------------------------------------------------
                                      Michigan -- 1.7%
       2,000,000             NR/Ba1   Flint Michigan Hospital Building Authority
                                      Revenue, 7.375%, 7/1/35                              $       2,335,760
       2,235,000             BB+/NR   Kent Hospital Finance Authority Revenue,
                                      6.25%, 7/1/40                                                2,347,041
         725,000              NR/NR   Michigan Public Educational Facilities Authority
                                      Revenue, 7.0%, 10/1/36                                         747,141
                                                                                           -----------------
                                                                                           $       5,429,942
------------------------------------------------------------------------------------------------------------
                                      Minnesota -- 0.4%
       1,000,000              NR/NR   Port Authority of the City of Bloomington,
                                      Minnesota Recovery Zone Facility Revenue,
                                      9.0%, 12/1/35                                        $       1,190,760
------------------------------------------------------------------------------------------------------------
                                      Missouri -- 1.1%
       1,000,000              NR/NR   Kansas City Tax Increment Financing Commission
                                      Tax Increment Revenue, 6.5%, 6/1/25                  $       1,040,520
       1,500,000(a)(d)        NR/Ca   St. Louis Industrial Development Authority
                                      Revenue, 7.2%, 12/15/28                                        448,335
       6,640,000(a)(d)        NR/Ca   St. Louis Industrial Development Authority
                                      Revenue, 7.25%, 12/15/35                                     1,984,630
                                                                                           -----------------
                                                                                           $       3,473,485
------------------------------------------------------------------------------------------------------------
                                      Montana -- 0.7%
       2,445,000(e)           NR/NR   Hardin Increment Industrial Infrastructure
                                      Development Revenue, 0.0%, 9/1/31                    $       2,043,140
       1,000,000(a)(d)        NR/NR   Two Rivers Authority Inc., Project Revenue,
                                      7.375%, 11/1/27                                                148,970
                                                                                           -----------------
                                                                                           $       2,192,110
------------------------------------------------------------------------------------------------------------
                                      Nevada -- 1.5%
       1,600,000(a)(d)        NR/NR   Director of the State of Nevada Department of
                                      Business & Industry Transportation Revenue,
                                      7.25%, 1/1/23                                        $              16
       1,000,000(a)           NR/NR   Director of the State of Nevada Department of
                                      Business & Industry Transportation Revenue,
                                      7.375%, 1/1/30                                                      10
       1,320,000(a)(d)        NR/NR   Director of the State of Nevada Department of
                                      Business & Industry Transportation Revenue,
                                      7.375%, 1/1/40                                                      13
       4,500,000              A-/A3   Reno Nevada Hospital Revenue, 5.25%, 6/1/41                  4,757,085
                                                                                           -----------------
                                                                                           $       4,757,124
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 17


Schedule of Investments | 9/30/12 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                      New Hampshire -- 0.4%
     $ 1,125,000              NR/NR   New Hampshire Health & Education Facilities
                                      Authority Revenue, 5.875%, 7/1/34                    $       1,168,459
------------------------------------------------------------------------------------------------------------
                                      New Jersey -- 12.0%
       2,500,000              NR/NR   Burlington County New Jersey Bridge Commission
                                      Revenue, 5.625%, 1/1/38                              $       2,588,775
       1,500,000              NR/NR   New Jersey Economic Development Authority
                                      Revenue, 10.5%, 6/1/32 (144A)                                1,658,220
       7,500,000              B-/B3   New Jersey Economic Development Authority
                                      Revenue, 5.75%, 9/15/27                                      7,513,875
       3,500,000(d)          AA-/WR   New Jersey State Turnpike Authority Transportation
                                      Revenue, RIB, 13.555%, 7/1/23 (144A)                         6,273,645
      15,375,000(e)         AA+/Aa1   New Jersey Transportation Trust Fund Authority
                                      Revenue, 0.0%, 12/15/27                                      8,429,036
       2,000,000              B-/B1   Tobacco Settlement Financing Corp., Revenue,
                                      4.625%, 6/1/26                                               1,854,080
       1,000,000(b)         AA+/Aaa   Tobacco Settlement Financing Corp., Revenue,
                                      6.25%, 6/1/43                                                1,040,760
       3,250,000(b)         AA+/Aaa   Tobacco Settlement Financing Corp., Revenue,
                                      6.75%, 6/1/39                                                3,393,423
       5,000,000(b)         AA+/Aaa   Tobacco Settlement Financing Corp., Revenue,
                                      7.0%, 6/1/41                                                 5,228,750
                                                                                           -----------------
                                                                                           $      37,980,564
------------------------------------------------------------------------------------------------------------
                                      New York -- 8.2%
       1,730,000              NR/NR   Dutchess County Industrial Development Agency
                                      Revenue, 7.5%, 3/1/29                                $       1,780,239
       7,000,000              BB/B2   New York City Industrial Development Agency
                                      Revenue, 5.25%, 12/1/32                                      6,900,950
       3,950,000              BB/B2   New York City Industrial Development Agency
                                      Revenue, 7.625%, 12/1/32                                     4,027,499
       5,000,000            AAA/Aaa   New York State Dormitory Authority Revenue,
                                      5.0%, 10/1/41                                                5,831,750
       2,000,000             NR/Ba1   New York State Dormitory Authority Revenue,
                                      6.125%, 12/1/29                                              2,209,660
       5,000,000            AAA/Aaa   New York State Environmental Facilities Corp.
                                      Water Revenue, 5.0%, 6/15/33                                 5,157,400
                                                                                           -----------------
                                                                                           $      25,907,498
------------------------------------------------------------------------------------------------------------
                                      North Carolina -- 1.6%
       5,010,000              NR/NR   Charlotte North Carolina Special Facilities
                                      Revenue, 7.75%, 2/1/28                               $       5,018,116
------------------------------------------------------------------------------------------------------------
                                      Ohio -- 1.8%
       1,500,000              NR/NR   Adams County Hospital Facilities Revenue,
                                      6.5%, 9/1/36                                         $       1,204,080
       5,000,000              B-/B3   Buckeye Tobacco Settlement Financing Authority
                                      Revenue, 6.5%, 6/1/47                                        4,412,200
                                                                                           -----------------
                                                                                           $       5,616,280
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

18 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12




------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                      Oklahoma -- 1.8%
     $ 2,220,000(a)           NR/WR   Tulsa Municipal Airport Trust Revenue,
                                      6.25%, 6/1/20                                        $       2,330,756
       3,000,000(a)(c)        NR/WR   Tulsa Municipal Airport Trust Revenue,
                                      7.75%, 6/1/35                                                3,436,860
                                                                                           -----------------
                                                                                           $       5,767,616
------------------------------------------------------------------------------------------------------------
                                      Oregon -- 0.7%
       2,000,000              A-/NR   Oregon State Facilities Authority Revenue,
                                      5.25%, 10/1/40                                       $       2,213,160
------------------------------------------------------------------------------------------------------------
                                      Pennsylvania -- 4.1%
       2,000,000           BBB-/Ba1   Pennsylvania Economic Development Financing
                                      Authority Revenue, 4.625%, 12/1/18                   $       2,029,660
       1,000,000              BB/NR   Pennsylvania Economic Development Financing
                                      Authority Revenue, 5.125%, 6/1/18                            1,000,350
       5,000,000            B-/Caa2   Pennsylvania Economic Development Financing
                                      Authority Solid Waste Disposal Revenue,
                                      6.0%, 6/1/31                                                 4,971,750
       5,000,000           BBB-/Ba1   Philadelphia Hospitals & Higher Education
                                      Facilities Authority Revenue, 5.0%, 7/1/34                   5,060,800
                                                                                           -----------------
                                                                                           $      13,062,560
------------------------------------------------------------------------------------------------------------
                                      Rhode Island -- 3.6%
       1,385,000(d)           NR/NR   Central Falls Rhode Island Detention Facility
                                      Corp. Revenue, 7.25%, 7/15/35                        $       1,198,607
       1,500,000              NR/NR   Rhode Island Health & Educational Building
                                      Corp., Revenue, 8.375%, 1/1/46                               1,760,100
       8,285,000             BB/Ba1   Tobacco Settlement Financing Corp. Revenue,
                                      6.25%, 6/1/42                                                8,408,529
                                                                                           -----------------
                                                                                           $      11,367,236
------------------------------------------------------------------------------------------------------------
                                      South Carolina -- 4.7%
       8,000,000(b)       BBB+/Baa1   South Carolina Jobs Economic Development
                                      Authority Revenue, 6.375%, 8/1/34                    $       8,410,720
       4,400,000(f)          BBB/WR   Tobacco Settlement Revenue Management
                                      Authority, 6.375%, 5/15/30                                   6,379,120
                                                                                           -----------------
                                                                                           $      14,789,840
------------------------------------------------------------------------------------------------------------
                                      Tennessee -- 2.9%
       5,000,000          BBB+/Baa1   Johnson City Health & Educational Facilities Board
                                      Hospital Revenue, 6.5%, 7/1/38                       $       5,988,550
       3,000,000            BBB+/NR   Sullivan County Health, Educational & Housing
                                      Facilities Board Revenue, 5.25%, 9/1/36                      3,141,540
                                                                                           -----------------
                                                                                           $       9,130,090
------------------------------------------------------------------------------------------------------------
                                      Texas -- 15.0%
       2,400,000            BB+/Ba1   Central Texas Regional Mobility Authority Revenue,
                                      6.75%, 1/1/41                                        $       2,768,832


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 19


Schedule of Investments | 9/30/12 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
Principal
Amount                S&P/Moody's
USD ($)               Ratings                                                              Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                      Texas -- (continued)
     $ 2,663,453(a)(d)        NR/NR   Gulf Coast Industrial Development Authority
                                      Revenue, 7.0%, 12/1/36                               $          24,743
      10,000,000              B-/B3   Houston Texas Airport System Special Facilities
                                      Revenue, 6.75%, 7/1/29                                      10,040,600
         595,000              NR/NR   IAH Public Facility Corp., Facilities Revenue,
                                      Series 2006, 6.0%, 5/1/16                                      580,506
       1,000,000              NR/NR   IAH Public Facility Corp., Facilities Revenue,
                                      Series 2006, 6.0%, 5/1/21                                      908,810
       1,350,000              NR/NR   IAH Public Facility Corp., Facilities Revenue,
                                      Series 2006, 6.125%, 5/1/26                                  1,190,754
       3,000,000              NR/NR   Jefferson County Industrial Development Corp.,
                                      Revenue, 8.25%, 7/1/32                                       2,808,900
       2,240,000            AA-/Aa3   Lower Colorado River Authority Power Revenue,
                                      5.0%, 5/15/31                                                2,243,584
         845,000              NR/NR   Lubbock Health Facilities Development Corp.,
                                      Nursing Home Revenue, 6.5%, 7/1/26                             891,906
       2,000,000              NR/NR   Lubbock Health Facilities Development Corp.,
                                      Nursing Home Revenue, 6.625%, 7/1/36                         2,090,860
       9,750,000            BBB+/A3   North Texas Tollway Authority Revenue,
                                      5.75%, 1/1/33                                               10,839,270
       1,711,000             NR/Aaa   Panhandle Regional Housing Finance Corp.,
                                      Multifamily Housing Revenue, 6.6%, 7/20/31                   1,799,493
       1,500,000              NR/NR   Red River Health Facilities Development Corp.,
                                      Revenue, 8.0%, 11/15/41                                      1,709,520
       1,000,000              A+/A1   Richardson Hospital Authority Revenue,
                                      6.0%, 12/1/34                                                1,027,190
       3,000,000              NR/NR   Sanger Industrial Development Corp., Revenue,
                                      8.0%, 7/1/38                                                 3,011,880
       1,000,000              NR/NR   Tarrant County Cultural Education Facilities
                                      Finance Corp., Revenue, 8.125%, 11/15/39                     1,114,350
       1,500,000              NR/NR   Tarrant County Cultural Education Facilities
                                      Finance Corp., Revenue, 8.25%, 11/15/44                      1,677,630
       1,000,000(a)(d)         D/NR   Texas Midwest Public Facility Corp., Revenue,
                                      9.0%, 10/1/30                                                  409,650
       2,500,000              NR/NR   Travis County Health Facilities Development Corp.
                                      Revenue, 7.125%, 1/1/46                                      2,623,100
                                                                                           -----------------
                                                                                           $      47,761,578
------------------------------------------------------------------------------------------------------------
                                      Virginia -- 0.8%
       2,000,000          BBB+/Baa1   Washington County Industrial Development
                                      Authority Revenue, 7.75%, 7/1/38                     $       2,492,980
------------------------------------------------------------------------------------------------------------
                                      Washington -- 3.8%
       1,125,000             BBB/A3   Tobacco Settlement Authority Revenue,
                                      6.5%, 6/1/26                                         $       1,166,051
       1,500,000            NR/Baa3   Washington State Health Care Facilities Authority
                                      Revenue, 5.5%, 12/1/39                                       1,603,665


The accompanying notes are an integral part of these financial statements.

20 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12




------------------------------------------------------------------------------------------------------------
Principal
Amount               S&P/Moody's
USD ($)              Ratings                                                               Value
------------------------------------------------------------------------------------------------------------
                                                                                  
                                      Washington -- (continued)
     $ 2,000,000           BBB/Baa2   Washington State Health Care Facilities
                                      Authority Revenue, 6.125%, 8/15/37                   $       2,210,900
       2,000,000           BBB/Baa2   Washington State Health Care Facilities
                                      Authority Revenue, 6.25%, 8/15/42                            2,209,740
       5,000,000              NR/NR   Washington State Housing Finance Committee
                                      Nonprofit Revenue, 5.625%, 1/1/27                            5,045,600
                                                                                           -----------------
                                                                                           $      12,235,956
------------------------------------------------------------------------------------------------------------
                                      West Virginia -- 0.3%
         750,000              NR/NR   West Virginia Hospital Finance Authority
                                      Hospital Revenue Bonds, 9.125%, 10/1/41              $         923,295
------------------------------------------------------------------------------------------------------------
                                      Wisconsin -- 3.1%
       2,900,000(g)           NR/NR   Aztalan Township, 7.5%, 5/1/18                       $              --
       2,500,000              NR/NR   Wisconsin Public Finance Authority Continuing
                                      Care Retirement Community Revenue,
                                      8.25%, 6/1/46                                                2,967,650
       1,000,000(b)           NR/NR   Wisconsin State Health & Educational Facilities
                                      Authority Revenue, 6.125%, 4/1/24                            1,080,620
       1,000,000(b)           NR/NR   Wisconsin State Health & Educational Facilities
                                      Authority Revenue, 6.25%, 4/1/34                             1,082,500
       1,500,000              A+/A1   Wisconsin State Health & Educational Facilities
                                      Authority Revenue, 6.625%, 2/15/39                           1,757,475
       1,500,000              NR/NR   Wisconsin State Public Finance Authority
                                      Revenue,
                                      8.375%, 6/1/20                                               1,516,920
       1,500,000              NR/NR   Wisconsin State Public Finance Authority
                                      Revenue,
                                      8.625%, 6/1/47                                               1,578,540
                                                                                           -----------------
                                                                                           $       9,983,705
------------------------------------------------------------------------------------------------------------
                                      TOTAL TAX EXEMPT OBLIGATIONS
                                      (Cost $399,251,144)                                  $     441,506,831
------------------------------------------------------------------------------------------------------------
                                      MUNICIPAL COLLATERALIZED DEBT
                                      OBLIGATION -- 2.6% of Net Assets
      13,000,000(c)(d)        NR/NR   Non-Profit Preferred Funding Trust I,
                                      6.75%, 9/15/37 (144A)                                $       8,210,150
------------------------------------------------------------------------------------------------------------
                                      TOTAL MUNICIPAL COLLATERALIZED DEBT
                                      OBLIGATION
                                      (Cost $13,000,000)                                   $       8,210,150
------------------------------------------------------------------------------------------------------------
                                      TAX EXEMPT MONEY MARKET MUTUAL
                                      FUND -- 0.8% of Net Assets
       2,600,000              NR/NR   BlackRock Liquidity Funds MuniFund Portfolio         $       2,600,000
------------------------------------------------------------------------------------------------------------
                                      TOTAL TAX EXEMPT MONEY MARKET
                                      MUTUAL FUND
                                      (Cost $2,600,000)                                    $       2,600,000
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 21


Schedule of Investments | 9/30/12 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
Principal
Amount              S&P/Moody's
USD ($)             Ratings                                                                Value
------------------------------------------------------------------------------------------------------------
                                                                                     
                                      TOTAL INVESTMENTS IN SECURITIES -- 142.6%
                                      (Cost $414,851,144) (h)(i)                           $     452,316,981
------------------------------------------------------------------------------------------------------------
                                      OTHER ASSETS AND LIABILITIES -- 4.7%                 $      14,893,358
------------------------------------------------------------------------------------------------------------
                                      PREFERRED SHARES AT REDEMPTION VALUE,
                                      INCLUDING DIVIDENDS PAYABLE -- (47.3)%               $    (150,008,301)
------------------------------------------------------------------------------------------------------------
                                      NET ASSETS APPLICABLE TO COMMON
                                      SHAREOWNERS --100.0%                                 $     317,202,037
============================================================================================================


NR         Security not rated by S&P or Moody's.

WR         Rating withdrawn by either S&P or Moody's.

(144A)     Security is exempt from registration under Rule 144A of the
           Securities Act of 1933. Such securities may be resold normally to
           qualified institutional buyers in a transaction exempt from
           registration. At September 30, 2012, the value of these securities
           amounted to $30,250,775, or 9.5% of total net assets applicable to
           common shareowners.

RIB        Residual Interest Bonds. The interest rate is subject to change
           periodically and inversely based upon prevailing market rates. The
           interest rate shown is the rate September 30, 2012.

(a)        Security is in default and is non-income producing.

(b)        Prerefunded bonds have been collateralized by U.S. Treasury or U.S.
           Government Agency securities which are held in escrow to pay interest
           and principal on the tax exempt issue and to retire the bonds in full
           at the earliest refunding date.

(c)        The interest rate is subject to change periodically. The interest is
           shown is the rate at September 30, 2012.

(d)        Indicates a security that has been deemed as illiquid. The aggregate
           cost of illiquid securities is $29,084,559. The aggregate fair value
           of $12,425,114 represents 3.9% of total net assets applicable to
           common shareowners.

(e)        Security issued with a zero coupon. Income is recognized through
           accretion of discount.

(f)        Escrow to maturity.

(g)        Security is valued using fair value methods.

The accompanying notes are an integral part of these financial statements.

22 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


(h)        The concentration of investments by type of obligation/ market sector
           is as follows:



                                                                        
             Insured
                FSA                                                         6.1%
                FSA-CR                                                      2.3
                AMBAC GO OF INSTN                                           2.3
                BHAC-CR MBIA                                                1.9
                AMBAC                                                       1.0
                GO OF INSTN                                                 0.6
                AGM                                                         0.5
                XLCA                                                        0.5
                GNMA COLL                                                   0.4
                ASSURED GTY                                                 0.4
                NATL-RE                                                     0.2
             Revenue Bonds:
                Health Revenue                                             20.7
                Tobacco Revenue                                            13.7
                Facilities Revenue                                         12.6
                Development Revenue                                         9.4
                Other Revenue                                               8.6
                Airport Revenue                                             6.1
                Education Revenue                                           4.5
                Pollution Control Revenue                                   3.8
                Transportation Revenue                                      2.4
                Water Revenue                                               1.9
                Utilities Revenue                                           0.1
                                                                          -----
                                                                          100.0%
                                                                          =====


(i)        At September 30, 2012, the net unrealized gain on investments based
           on cost for federal tax purposes of $414,583,161 was as follows:



                                                                                   
                Aggregate gross unrealized gain for all investments in which there
                   is an excess of value over tax cost                                $  59,000,934
                Aggregate gross unrealized loss for all investments in which there
                   is an excess of tax cost over value                                  (21,267,114)
                                                                                      -------------
                Net unrealized gain                                                   $  37,733,820
                                                                                      =============


For financial reporting purposes net unrealized gain on investments was
$37,465,837 and cost of investments aggregated $414,851,144.

Purchases and sales of securities (excluding temporary cash investments) for the
six months ended September 30, 2012 aggregated $28,076,435 and $12,280,594,
respectively.

Principal amounts are denominated in U.S. dollars unless otherwise noted.

The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 23


Schedule of Investments | 9/30/12 (unaudited) (continued)

Various inputs are used in determining the value of the Trust's
investments. These inputs are summarized in the three broad levels below.

   Level 1 - quoted prices in active markets for identical securities
   Level 2 - other significant observable inputs (including quoted prices for
             similar securities, interest rates, prepayment speeds credit risks,
             etc.)
   Level 3 - significant unobservable inputs (including the Trust's own
             assumptions in determining fair value of investments)

Generally, equity securities are categorized as Level 1, fixed income securities
and senior loans are categorized as Level 2, and securities valued using fair
value methods (other than prices supplied by independent pricing services) are
categorized as Level 3. See Notes to Financial Statements -- Note 1A

The following is a summary of the inputs used as of September 30, 2012, in
valuing the Trust's investments.



------------------------------------------------------------------------------------------------------
                                            Level 1          Level 2          Level 3    Total
------------------------------------------------------------------------------------------------------
                                                                             
Tax exempt obligations                      $          --    $ 441,506,831    $  --      $ 441,506,831
Municipal collateralized debt obligation               --        8,210,150       --          8,210,150
Tax exempt money market mutual fund             2,600,000               --       --          2,600,000
------------------------------------------------------------------------------------------------------
   Total                                    $   2,600,000    $ 449,716,981    $  --      $ 452,316,981
======================================================================================================


The following is a reconciliation of assets valued using significant
unobservable inputs (level 3):



-----------------------------------------------------------------------------------------------------------------------
                                     Change in
              Balance     Realized   Unrealized                           Accrued     Transfers    Transfers    Balance
              as of       gain       appreciation                         discounts/  in to        out of       as of
              3/31/12     (loss)     (depreciation)   Purchases   Sales   premiums    Level 3*     Level 3*     9/30/12
-----------------------------------------------------------------------------------------------------------------------
                                                                                     
Tax exempt
  obligations $ --        $ --       $ --             $ --        $ --    $ --        $ --         $ --         $ --**
-----------------------------------------------------------------------------------------------------------------------
Total         $ --        $ --       $ --             $ --        $ --    $ --        $ --         $ --         $ --**
-----------------------------------------------------------------------------------------------------------------------


*   Transfers are calculated on the end of period value.
**  Azatlan Township is fair valued at $0.

The accompanying notes are an integral part of these financial statements.

24 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Statement of Assets and Liabilities | 9/30/12 (unaudited)



                                                                                     
ASSETS:
   Investments in securities, at value (cost $414,851,144)                              $ 452,316,981
   Cash                                                                                     2,243,118
   Receivables for --
     Investment securities sold                                                             4,126,225
     Interest receivable                                                                    8,811,105
   Reinvestment of distributions                                                              158,148
   Prepaid expenses                                                                            22,999
   Other assets                                                                                24,000
------------------------------------------------------------------------------------------------------
       Total assets                                                                     $ 467,702,576
------------------------------------------------------------------------------------------------------
LIABILITIES:
   Due to affiliates                                                                    $     220,880
   Administration fee                                                                          73,469
   Accrued expenses                                                                           192,896
   Other liabilities                                                                            4,993
------------------------------------------------------------------------------------------------------
       Total liabilities                                                                $     492,238
------------------------------------------------------------------------------------------------------
PREFERRED SHARES AT REDEMPTION VALUE:
   $25,000 liquidation value per share applicable to 6,000 shares,
     including dividends payable of $8,301                                              $ 150,008,301
------------------------------------------------------------------------------------------------------
NET ASSETS APPLICABLE TO COMMON SHAREOWNERS:
   Paid-in capital                                                                      $ 331,376,245
   Undistributed net investment income                                                      7,999,688
   Accumulated net realized loss on investments                                           (59,639,733)
   Net unrealized gain on investments                                                      37,465,837
------------------------------------------------------------------------------------------------------
       Net assets applicable to common shareowners                                      $ 317,202,037
======================================================================================================
NET ASSET VALUE PER COMMON SHARE:
No par value (unlimited number of shares authorized)
   Based on $317,202,037/23,345,818 common shares                                       $       13.59
======================================================================================================


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 25


Statement of Operations (unaudited)

For the Six Months Ended 9/30/12



                                                                                  
INVESTMENT INCOME:
   Interest                                                                             $  14,418,063
------------------------------------------------------------------------------------------------------
EXPENSES:
   Management fees                                                   $    1,382,372
   Administration fees                                                      100,227
   Transfer agent fees and expenses                                           9,174
   Shareowner communication expenses                                          7,236
   Auction agent fees                                                       186,536
   Custodian fees                                                             4,147
   Registration fees                                                         12,180
   Professional fees                                                        167,996
   Printing expenses                                                         14,219
   Trustees' fees                                                             8,464
   Pricing fees                                                              15,105
   Miscellaneous                                                             39,202
------------------------------------------------------------------------------------------------------
     Total expenses                                                                     $   1,946,858
------------------------------------------------------------------------------------------------------
       Net investment income                                                            $  12,471,205
------------------------------------------------------------------------------------------------------
REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS:
   Net realized gain from investments                                $    1,135,900
   Change in net unrealized gain from investments                    $   16,555,325
------------------------------------------------------------------------------------------------------
       Net gain on investments                                                          $  17,691,225
------------------------------------------------------------------------------------------------------
DISTRIBUTIONS TO PREFERRED SHAREOWNERS FROM
NET INVESTMENT INCOME:                                                                  $    (242,936)
------------------------------------------------------------------------------------------------------
   Net increase in net assets applicable to common shareowners
     resulting from operations                                                          $  29,919,494
======================================================================================================


The accompanying notes are an integral part of these financial statements.

26 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Statements of Changes in Net Assets



------------------------------------------------------------------------------------------------------
                                                                     Six Months
                                                                     Ended
                                                                     9/30/12            Year Ended
                                                                     (unaudited)        3/31/12
------------------------------------------------------------------------------------------------------
                                                                                  
FROM OPERATIONS:
Net investment income                                                $   12,471,205     $  25,127,884
Net realized gain (loss) on investments                                   1,135,900        (5,391,166)
Change in net unrealized gain (loss) on investments                      16,555,325        41,794,771
Distributions to preferred shareowners from
   net investment income                                                   (242,936)         (417,488)
------------------------------------------------------------------------------------------------------
     Net increase in net assets applicable to common
       shareowners resulting from operations                         $   29,919,494     $  61,114,001
------------------------------------------------------------------------------------------------------
DISTRIBUTIONS TO COMMON SHAREOWNERS:
Net investment income ($0.57 and $1.31 per share, respectively)      $  (13,285,744)    $ (30,307,904)
------------------------------------------------------------------------------------------------------
       Total distributions to common shareowners                     $  (13,285,744)    $ (30,307,904)
------------------------------------------------------------------------------------------------------
FROM TRUST SHARE TRANSACTIONS:
Reinvestment of distributions                                        $      931,061     $   1,961,141
------------------------------------------------------------------------------------------------------
     Net increase in net assets applicable to common
       shareowners from Trust share transactions                     $      931,061     $   1,961,141
------------------------------------------------------------------------------------------------------
     Net increase in net assets applicable to common
       shareowners                                                   $   17,564,811     $  32,767,238
NET ASSETS APPLICABLE TO COMMON SHAREOWNERS:
Beginning of period                                                     299,637,226       266,869,988
------------------------------------------------------------------------------------------------------
End of period                                                        $  317,202,037     $ 299,637,226
------------------------------------------------------------------------------------------------------
Undistributed net investment income                                  $    7,999,688     $   9,057,163
======================================================================================================


The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 27


Financial Highlights



----------------------------------------------------------------------------------------------------------------------------
                                                           Six Months
                                                           Ended        Year      Year       Year      Year       Year
                                                           9/30/12      Ended     Ended      Ended     Ended      Ended
                                                           (unaudited)  3/31/12   3/31/11    3/31/10   3/31/09    3/31/08
----------------------------------------------------------------------------------------------------------------------------
                                                                                                
Per Share Operating Performance
Net asset value, beginning of period                       $12.87       $11.54    $ 12.24    $ 9.23    $ 13.54    $ 15.91
----------------------------------------------------------------------------------------------------------------------------
Increase (decrease) from investment operations:(a)
   Net investment income                                   $ 0.53       $ 1.08    $  1.18    $ 1.18    $  1.22    $  1.29
   Net realized and unrealized gain (loss) on
     investments and interests rate swaps                    0.77         1.58      (0.79)     2.83      (4.43)     (2.51)
Distributions to preferred shareowners from:
   Net investment income                                    (0.01)       (0.02)     (0.03)    (0.04)     (0.20)     (0.26)
----------------------------------------------------------------------------------------------------------------------------
     Net increase (decrease) from investment operations    $ 1.29       $ 2.64    $  0.36    $ 3.97    $ (3.41)   $ (1.48)
Distributions to common shareowners from:
   Net investment income                                    (0.57)       (1.31)     (1.06)    (0.96)     (0.90)     (0.89)
----------------------------------------------------------------------------------------------------------------------------
Net increase (decrease) in net asset value                 $ 0.72       $ 1.33    $ (0.70)   $ 3.01    $ (4.31)   $ (2.37)
----------------------------------------------------------------------------------------------------------------------------
Net asset value, end of period(b)                          $13.59       $12.87    $ 11.54    $12.24    $  9.23    $ 13.54
----------------------------------------------------------------------------------------------------------------------------
Market value, end of period(b)                             $15.99       $14.72    $ 12.64    $13.10    $  9.04    $ 13.74
============================================================================================================================
Total return at market value(c)                             12.69%       28.48%      4.97%    57.76%    (28.40)%    (6.51)%
Ratios to average net assets of common shareowners:
   Net expenses (d)                                          1.25%(e)     1.36%      1.35%     1.41%      1.38%      1.13%
   Net investment income before preferred share
     distributions                                           8.04%(e)     8.73%      9.54%    10.66%     10.70%      8.27%
   Preferred share distributions                             0.16%(e)     0.15%      0.25%     0.33%      1.76%      1.64%
   Net investment income available to common shareowners     7.88%(e)     8.58%      9.29%    10.33%      8.94%      6.63%
Portfolio turnover                                              3%          15%        10%        8%        24%        12%


The accompanying notes are an integral part of these financial statements.

28 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12




------------------------------------------------------------------------------------------------------------------------------------
                                                                Six Months
                                                                Ended         Year       Year       Year        Year      Year
                                                                9/30/12       Ended      Ended      Ended       Ended     Ended
                                                                (unaudited)   3/31/12    3/31/11    3/31/10     3/31/09   3/31/08
------------------------------------------------------------------------------------------------------------------------------------
                                                                                                        
Net assets of common shareowners, end of period (in thousands)  $317,202      $299,637   $266,870   $281,551   $211,147   $308,500
Preferred shares outstanding (in thousands)                     $150,008      $150,000   $150,000   $150,000   $150,000   $150,000
Asset coverage per preferred share, end of period               $ 77,870      $ 74,941   $ 69,479   $ 71,926   $ 60,192   $ 76,427
Average market value per preferred share (f)                    $ 25,001      $ 25,000   $ 25,000   $ 25,000   $ 25,000   $ 25,000
Liquidation value, including dividends payable, per preferred
   share                                                        $ 25,003      $ 25,001   $ 25,001   $ 25,001   $ 25,001   $ 25,010
Ratios to average net assets of common shareowners before
   waivers and reimbursement of expenses
   Net expenses (d)                                                 1.25%(e)      1.36%      1.35%      1.41%      1.38%      1.13%
   Net investment income before preferred share distributions       8.04%(e)      8.73%      9.54%     10.66%     10.70%      8.27%
   Preferred share distributions                                    0.16%(e)      0.15%      0.25%      0.33%      1.76%      1.64%
   Net investment income available to common shareowners            7.88%(e)      8.58%      9.29%     10.33%      8.94%      6.63%
====================================================================================================================================


(a) The per common share data presented above is based upon the average common
    shares outstanding for the periods presented.

(b) Net asset value and market value are published in Barron's on Saturday, The
    Wall Street Journal on Monday and The New York Times on Monday and Saturday.

(c) Total investment return is calculated assuming a purchase of common shares
    at the current market value on the first day and a sale at the current
    market value on the last day of the periods reported. Dividends and
    distributions, if any, are assumed for purposes of this calculation to be
    reinvested at prices obtained under the Trust's dividend reinvestment plan.
    Total investment return does not reflect brokerage commissions. Past
    performance is not a guarantee of future results.

(d) Expense ratios do not reflect the effect of distribution payments to
    preferred shareowners.

(e) Annualized.

(f) Market value is redemption value without an active market.

The information above represents the audited operating performance data for a
share of common stock outstanding, total investment return, ratios to average
net assets and other supplemental data for the periods indicated. This
information has been determined based upon financial information provided in the
financial statements and market value data for the Trust's common shares.

The accompanying notes are an integral part of these financial statements.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 29


Notes to Financial Statements | 9/30/12 (unaudited)

1. Organization and Significant Accounting Policies

Pioneer Municipal High Income Advantage Trust (the Trust) was organized as a
Delaware statutory trust on August 6, 2003. Prior to commencing operations on
October 20, 2003, the Trust had no operations other than matters relating to its
organization and registration as a diversified, closed-end management investment
company under the Investment Company Act of 1940, as amended. The investment
objective of the Trust is to seek a high level of current income exempt from
regular federal income tax, and the Trust may, as a secondary objective, also
seek capital appreciation to the extent that it is consistent with its primary
investment objective.

The Trust's financial statements have been prepared in conformity with U.S.
generally accepted accounting principles that require the management of the
Trust to, among other things, make estimates and assumptions that affect the
reported amounts of assets and liabilities, the disclosure of contingent assets
and liabilities at the date of the financial statements, and the reported
amounts of income, expenses and gain or loss on investments during the reporting
period. Actual results could differ from those estimates.

The following is a summary of significant accounting policies followed by the
Trust in the preparation of its financial statements, which are consistent with
those policies generally accepted in the investment company industry:

A.  Security Valuation

    Security transactions are recorded as of trade date. Fixed income securities
    with remaining maturity of more than sixty days are valued at prices
    supplied by independent pricing services, which consider such factors as
    market prices, market events, quotations from one or more brokers, Treasury
    spreads, yields, maturities and ratings. Valuations may be supplemented by
    dealers and other sources, as required. The values of interest rate swaps
    are determined by obtaining dealer quotations. Equity securities that have
    traded on an exchange are valued at the last sale price on the principal
    exchange where they are traded. Equity securities that have not traded on
    the date of valuation, or securities for which sale prices are not
    available, generally are valued using the mean between the last bid and
    asked prices. Short-term fixed income securities with remaining maturities
    of sixty days or less generally are valued at amortized cost. Money market
    mutual funds are valued at net asset value.

30 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


    Securities for which independent pricing services are unable to supply
    prices or for which market prices and/or quotations are not readily
    available or are considered to be unreliable are valued using fair value
    methods pursuant to procedures adopted by the Board of Trustees. The Trust
    may use fair value methods if it is determined that a significant event has
    occurred after the close of the exchange or market on which the security
    trades and prior to the determination of the Trust's net asset value.
    Examples of a significant event might include political or economic news,
    corporate restructurings, natural disasters, terrorist activity or trading
    halts. Thus, the valuation of the Trust's securities may differ from
    exchange prices.

    At September 30, 2012, one security was valued using fair value methods (in
    addition to securities valued using prices supplied by independent pricing
    services) representing 0.0% of net assets. Inputs used when applying fair
    value methods to value a security may include credit ratings, the financial
    condition of the company, current market conditions and comparable
    securities.

    Discount and premium on debt securities are accreted or amortized,
    respectively, daily into interest income on a yield-to-maturity basis with a
    corresponding increase or decrease in the cost basis of the security.
    Interest income, including interest on income bearing cash accounts, is
    recorded on an accrual basis.

    Dividend income is recorded on the ex-dividend date, except that certain
    dividends from foreign securities where the ex-dividend date may have passed
    are recorded as soon as the Trust becomes aware of the ex-dividend data in
    the exercise of reasonable diligence.

    Gains and losses on sales of investments are calculated on the identified
    cost method for both financial reporting and federal income tax purposes.

B.  Federal Income Taxes

    It is the Trust's policy to comply with the requirements of the Internal
    Revenue Code applicable to regulated investment companies and to distribute
    all of its taxable income and net realized capital gains, if any, to its
    shareowners. Therefore, no federal income tax provision is required. Tax
    years for the prior three fiscal years remain subject to examination by
    federal and state tax authorities.

    The amounts and characterizations of distributions to shareowners for
    financial reporting purposes are determined in accordance with federal
    income tax rules. Therefore, the sources of the Trust's distributions may be
    shown in the accompanying financial statements as from or in excess of net
    investment income or as from net realized gain (loss) on investment
    transactions, or as from paid-in capital, depending on the type of book/tax
    differences that may exist.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 31


    The tax character of current year distributions payable to common and
    preferred shareowners will be determined at the end of the current taxable
    year. The tax character of distributions paid during the year ended March
    31, 2012 was as follows:



--------------------------------------------------------------------------------
                                                                            2012
--------------------------------------------------------------------------------
                                                                
Distribution paid from:
Tax exempt income                                                  $  26,664,988
Ordinary income                                                        4,060,404
--------------------------------------------------------------------------------
     Total taxable distribution                                    $  30,725,392
================================================================================


    The following shows the components of distributable earnings (losses) on a
    federal income tax basis at March 31, 2012:



--------------------------------------------------------------------------------
                                                                           2012
--------------------------------------------------------------------------------
                                                               
Distributable earnings:
Undistributed tax-exempt income                                   $   9,047,860
Undistributed ordinary income                                           960,017
Capital loss carryforward                                           (55,783,255)
Post-October loss deferred                                           (6,203,339)
Dividends payable                                                        (7,736)
Unrealized appreciation                                              21,178,495
--------------------------------------------------------------------------------
     Total                                                        $ (30,807,958)
================================================================================


    The difference between book-basis and tax-basis unrealized appreciation is
    primarily attributable to the difference between book and tax amortization
    methods for premiums and discounts on fixed income securities, the
    difference between book and tax accounting for swap agreements, book/tax
    difference in accrual of income on securities in default, and other
    temporary differences.

C.  Automatic Dividend Reinvestment Plan

    All common shareowners whose shares are registered in their own names
    automatically participate in the Automatic Dividend Reinvestment Plan (the
    Plan), under which participants receive all dividends and capital gain
    distributions (collectively, dividends) in full and fractional common shares
    of the Trust in lieu of cash. Shareowners may elect not to participate in
    the Plan. Shareowners not participating in the Plan receive all dividends
    and capital gain distributions in cash. Participation in the Plan is
    completely voluntary and may be terminated or resumed at any time without
    penalty by notifying American Stock Transfer & Trust Company, the agent for
    shareowners in administering the Plan (the Plan Agent), in writing prior to
    any dividend record date; otherwise such termination or resumption will be
    effective with respect to any subsequently declared dividend or other
    distribution.

32 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


    If a shareowner's shares are held in the name of a brokerage firm, bank or
    other nominee, the shareowner can ask the firm or nominee to participate in
    the Plan on the shareowner's behalf. If the firm or nominee does not offer
    the Plan, dividends will be paid in cash to the shareowner of record. A firm
    or nominee may reinvest a shareowner's cash dividends in common shares of
    the Trust on terms that differ from the terms of the Plan.

    Whenever the Trust declares a dividend on common shares payable in cash,
    participants in the Plan will receive the equivalent in common shares
    acquired by the Plan Agent either (i) through receipt of additional unissued
    but authorized common shares from the Trust or (ii) by purchase of
    outstanding common shares on the New York Stock Exchange or elsewhere. If,
    on the payment date for any dividend, the net asset value per common share
    is equal to or less than the market price per share plus estimated brokerage
    trading fees (market premium), the Plan Agent will invest the dividend
    amount in newly issued common shares. The number of newly issued common
    shares to be credited to each account will be determined by dividing the
    dollar amount of the dividend by the net asset value per common share on the
    date the shares are issued, provided that the maximum discount from the then
    current market price per share on the date of issuance does not exceed 5%.
    If, on the payment date for any dividend, the net asset value per common
    share is greater than the market value (market discount), the Plan Agent
    will invest the dividend amount in common shares acquired in open-market
    purchases. There are no brokerage charges with respect to newly issued
    common shares. However, each participant will pay a pro rata share of
    brokerage trading fees incurred with respect to the Plan Agent's open-market
    purchases. Participating in the Plan does not relieve shareowners from any
    federal, state or local taxes which may be due on dividends paid in any
    taxable year. Shareowners holding Plan shares in a brokerage account may not
    be able to transfer the shares to another broker and continue to participate
    in the Plan.

D.  Risks

    At times, the Trust's investments may represent industries or industry
    sectors that are interrelated or have common risks, making the Trust more
    susceptible to any economic, political, or regulatory developments or other
    risks affecting those industries and sectors. Information regarding the
    Trust's principal risks is contained in the Trust's original offering
    prospectus, with additional information included in the Trust's shareowner
    reports issued from time to time. Please refer to those documents when
    considering the Trust's principal risks.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 33


    The Trust may invest in both investment grade and below investment grade
    (high-yield) municipal securities with a broad range of maturities and
    credit ratings. Debt securities rated below investment grade are commonly
    referred to as "junk bonds" and are considered speculative. These securities
    involve greater risk of loss, are subject to greater price volatility, and
    are less liquid, especially during periods of economic uncertainty or
    change, than higher rated debt securities.

2.  Management Agreement

Pioneer Investment Management, Inc. (PIM), the Trust's investment adviser, a
wholly owned indirect subsidiary of UniCredit S.p.A. (UniCredit), manages the
Trust's portfolio. Management fees payable under the Trust's Advisory Agreement
with PIM are calculated daily at the annual rate of 0.60% of the Trust's average
daily managed assets. "Managed assets" means (a) the total assets of the Trust,
including any form of investment leverage, minus (b) all accrued liabilities
incurred in the normal course of operations, which shall not include any
liabilities or obligations attributable to investment leverage obtained through
(i) indebtedness of any type (including, without limitation, borrowing through a
credit facility of the issuance of debt securities), (ii) the issuance of
preferred stock or other similar preference securities, and/or (iii) any other
means. For the period ended September 30, 2012, the net management fee was 0.60%
of the Trust's average daily managed assets, which was equivalent to 0.91% of
the Trust's average daily net assets attributable to the common shareowners.

In addition, under PIM's management and administration agreements, certain other
services and costs are paid by PIM and reimbursed by the Trust. At September 30,
2012, $294,349 was payable to PIM related to management costs, administrative
costs and certain other reimbursements and is included in "Due to affiliates"
and "Administration fee" on the Statement of Assets and Liabilities.

Effective April 1, 2012, PIM has retained Brown Brothers Harriman & Co. (BBH) to
provide certain administrative and accounting services to the Trust on its
behalf. For such services, PIM pays BBH a monthly fee at an annual rate of
0.025% of the Trust's average daily managed assets subject to a minimum monthly
fee of $6,250. Previously, PIM had retained State Street Bank and Trust Company
(State Street) to provide such services. PIM paid State Street a monthly fee at
an annual rate of 0.07% of the Trust's average daily managed assets in excess up
to $500 million, subject to a minimum monthly fee of $10,000. Neither BBH nor
State Street received compensation directly from the Trust for providing such
services.

34 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


3. Transfer Agents

Pioneer Investment Management Shareholder Services, Inc. (PIMSS), a wholly owned
indirect subsidiary of UniCredit, through a sub-transfer agency agreement with
American Stock Transfer & Trust Company, provides substantially all transfer
agent and shareowner services related to the Trust's common shares at negotiated
rates. Deutsche Bank Trust Company Americas (Deutsche Bank) is the transfer
agent, registrar, dividend paying agent and auction agent with respect to the
Trust's Auction Preferred Shares (APS). The Trust pays Deutsche Bank an annual
fee, as is agreed to from time to time by the Trust and Deutsche Bank, for
providing such services.

In addition, the Trust reimburses PIMSS for out-of-pocket expenses incurred by
PIMSS related to shareowner communications activities such as proxy and
statement mailings and outgoing phone calls.

4. Expense Offset Agreements

The Trust has entered into an arrangement with its custodian whereby credits
realized as a result of uninvested cash balances are used to reduce a portion of
the Trust's custodian expenses. For the six months ended September 30, 2012, the
Trust expenses were not reduced under such arrangement.

5. Interest Rate Swaps

The Trust may enter into interest rate swap transactions to attempt to protect
itself from increasing dividend or interest expense on its leverage resulting
from increasing short-term interest rates. The cost of leverage may rise with an
increase in interest rates, generally having the effect of lower yields and
potentially lower dividends to common shareowners. Interest rate swaps can be
used to "lock in" the cost of leverage and reduce the negative impact that
rising short-term interest rates would have on the Trust's leveraging costs.

An interest rate swap is an agreement between two parties, which involves
exchanging floating rate and fixed rate interest payments for a specified period
of time. Interest rate swaps involve the accrual of the net interest payments
between the parties on a daily basis, with the net amount recorded within the
unrealized appreciation/depreciation of interest rate swaps on the Statement of
Assets and Liabilities. Once the interim payments are settled in cash, at the
predetermined dates specified in the agreement, the net amount is recorded as
realized gain or loss from interest rate swaps on the Statement of Operations.
During the term of the swap, changes in the value of the swap are recognized as
unrealized gains and losses by "marking-to-market" the value of the swap based
on values obtained from dealer quotations. When the swap is terminated, the
Trust will record a realized gain or loss equal to the difference, if any,
between the proceeds from (or cost of) closing the contract and the cost basis
of the contract. The Trust is exposed to credit risk in the event of
non-performance by

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 35


the other party to the interest rate swap. Risks may also arise with regard to
market movements in the value of the swap arrangement that do not exactly offset
the changes in the related dividend requirement or interest expense on the
Trust's leverage.

There were no interest rate swap contracts open during the six
months ended September 30, 2012 or outstanding at September 30, 2012.

6. Trust Shares

There are an unlimited number of common shares of beneficial interest
authorized.

Transactions in common shares of beneficial interest for the periods
ended September 30, 2012 and March 31, 2012 were as follows:



--------------------------------------------------------------------------------
                                                          9/30/12        3/31/12
--------------------------------------------------------------------------------
                                                                
Shares outstanding at beginning of period              23,282,302     23,133,791
Reinvestment of distributions                              63,516        148,511
--------------------------------------------------------------------------------
Shares outstanding at end of period                    23,345,818     23,282,302
================================================================================


The Trust may classify or reclassify any unissued shares of beneficial interest
into one or more series of preferred shares of beneficial interest. As of
September 30, 2012, there were 6,000 APS as follows: Series A -- 3,000 and
Series B -- 3,000.

Dividends on Series A and Series B are cumulative at a rate which is to be reset
every seven days based on the results of an auction. An auction fails if there
are more APS offered for sale than there are buyers. When an auction fails, the
dividend rate for the period will be the maximum rate on the auction dates
described in the prospectus for the APS. Preferred shareowners are not able to
sell their APS at an auction if the auction fails. Since February 2008, the
Trust's auctions related to the APS have failed. The maximum rate for each
series is 125% of the 7 day commercial paper rate or adjusted Kenny rate.
Dividend rates on APS ranged from 0.26% to 0.45% during the period ended
September 30, 2012.

The Trust may not declare dividends or make other distributions on its common
shares or purchase any such shares if, at the time of the declaration,
distribution or purchase, the Trust does not comply with the asset coverage
ratios described in the prospectus for the APS.

36 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


The APS are redeemable at the option of the Trust, in whole or in part, on any
dividend payment date at $25,000 per share plus any accumulated or unpaid
dividends, whether or not declared. The APS are also subject to mandatory
redemption at $25,000 per share plus any accumulated or unpaid dividends,
whether or not declared, if certain requirements relating to the composition of
the assets and liabilities of the Trust as set forth in the Statement of
Preferences are not satisfied.

The holders of APS have voting rights equal to the holders of the Trust's common
shares (one vote per share) and will vote together with holders of the common
shares as a single class. Holders of APS are also entitled to elect two of the
Trust's Trustees. In addition, the Investment Company Act of 1940, as amended,
requires that along with approval by shareowners that might otherwise be
required, the approval of the holders of a majority of any outstanding preferred
shares, voting separately as a class, would be required to (a) adopt any plan of
reorganization that would adversely affect the preferred shares and (b) take any
action requiring a vote of security holders, including, among other things,
changes in the Trust's subclassification as a closed-end management investment
company or changes in its fundamental investment restrictions.

7. Subsequent Events

The Board of Trustees of the Trust declared on October 4, 2012 a dividend from
undistributed net investment income of $0.095 per common share payable October
31, 2012, to common shareowners of record on October 16, 2012.

Subsequent to September 30, 2012, dividends declared and paid on preferred
shares totaled $45,503 in aggregate for the two outstanding preferred share
series through November 7, 2012.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 37


ADDITIONAL INFORMATION (unaudited)

During the period, there have been no material changes in the Trust's investment
objective or fundamental policies that have not been approved by the
shareowners. There have been no changes in the Trust's charter or By-Laws that
would delay or prevent a change in control of the Trust which has not been
approved by the shareowners. During the period, there have been no changes in
the principal risk factors associated with investment in the Trust. There were
no changes in the persons who are primarily responsible for the day-to-day
management of the Trust's portfolio.

Notice is hereby given in accordance with Section 23(c) of the Investment
Company Act of 1940 that the Trust may purchase, from time to time, its common
shares in the open market.

Results of Shareholder Meeting (unaudited)

At the annual meeting of shareowners held on September 18, 2012, shareowners of
Pioneer Municipal High Income Advantage were asked to consider the proposal
described below. A report of the total votes cast by the Trust's shareholders
follows:

Proposal 1 -- To elect Class III Trustee.



--------------------------------------------------------------------------------
Nominee                                    For                       Withheld
--------------------------------------------------------------------------------
                                                               
Thomas J. Perna                            20,967,863.608            589,715.000
Marguerite A. Piret*                            3,635.000                 53.000


* Elected by preferred shares only

38 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


Trustees, Officers and Service Providers

Trustees                               Officers
Thomas J. Perna, Chairman              John F. Cogan, Jr., President*
David R. Bock                          Daniel K. Kingsbury, Executive
John F. Cogan, Jr.                        Vice President
Benjamin M. Friedman                   Mark E. Bradley, Treasurer**
Margaret B.W. Graham                   Christopher J. Kelley, Secretary
Daniel K. Kingsbury
Marguerite A. Piret
Stephen K. West

Investment Adviser and Administrator
Pioneer Investment Management, Inc.

Custodian and Sub-Administrator
Brown Brothers Harriman & Co.

Principal Underwriter
Pioneer Funds Distributor, Inc.

Legal Counsel
Bingham McCutchen LLP

Shareowner Services and Transfer Agent
Pioneer Investment Management Shareholder Services, Inc.

Proxy Voting Policies and Procedures of the Fund are available without charge,
upon request, by calling our toll free number (1-800-225-6292). Information
regarding how the Fund voted proxies relating to portfolio securities during the
most recent 12-month period ended June 30 is publicly available to shareowners
at us.pioneerinvestments.com. This information is also available on the
Securities and Exchange Commission's web site at http://www.sec.gov.

*   Chief Executive Officer of the Trust
**  Chief Financial and Accounting Officer of the Trust

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 39


                           This page for your notes.

40 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


                           This page for your notes.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 41


                           This page for your notes.

42 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


                           This page for your notes.

  Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12 43


                           This page for your notes.

44 Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/12


How to Contact Pioneer

We are pleased to offer a variety of convenient ways for you to contact us for
assistance or information.

You can call American Stock Transfer & Trust Company (AST) for:
--------------------------------------------------------------------------------
Account Information                              1-800-225-6292

Or write to AST:
--------------------------------------------------------------------------------
For                                              Write to

General inquiries, lost dividend checks,         American Stock
change of address, lost stock certificates,      Transfer & Trust
stock transfer                                   Operations Center
                                                 6201 15th Ave.
                                                 Brooklyn, NY 11219

Dividend reinvestment plan (DRIP)                American Stock
                                                 Transfer & Trust
                                                 Wall Street Station
                                                 P.O. Box 922
                                                 New York, NY 10269-0560

Website                                          www.amstock.com

For additional information, please contact your investment advisor or visit our
web site us.pioneerinvestments.com.

The Trust files a complete schedule of investments with the Securities and
Exchange Commission for the first and third quarters for each fiscal year on
Form N-Q. Shareowners may view the filed Form N-Q by visiting the Commission's
web site at www.sec.gov. The filed form may also be viewed and copied at the
Commission's Public Reference Room in Washington, DC. Information regarding the
operations of the Public Reference Room may be obtained by calling
1-800-SEC-0330.


[LOGO] PIONEER
       Investments(R)

Pioneer Investment Management, Inc.
60 State Street
Boston, MA 02109

us.pioneerinvestments.com

Securities offered through Pioneer Funds Distributor, Inc.
60 State Street, Boston, MA 02109
Underwriter of Pioneer Mutual Funds, Member SIPC
(C) 2012 Pioneer Investments  19435-06-1112


ITEM 2. CODE OF ETHICS.

(a) Disclose whether, as of the end of the period covered by the report, the
registrant has adopted a code of ethics that applies to the registrant's
principal executive officer, principal financial officer, principal accounting
officer or controller, or persons performing similar functions, regardless of
whether these individuals are employed by the registrant or a third party.  If
the registrant has not adopted such a code of ethics, explain why it has not
done so.

The registrant has adopted, as of the end of the period covered by this report,
a code of ethics that applies to the registrant's principal executive officer,
principal financial officer, principal accounting officer and controller.

(b) For purposes of this Item, the term "code of ethics" means written standards
that are reasonably designed to deter wrongdoing and to promote:

        (1) Honest and ethical conduct, including the ethical handling of actual
        or apparent conflicts of interest between personal and professional
        relationships;

        (2) Full, fair, accurate, timely, and understandable disclosure in
        reports and documents that a registrant files with, or submits to, the
        Commission and in other public communications made by the registrant;

        (3) Compliance with applicable governmental laws, rules, and
        regulations;

        (4) The prompt internal reporting of violations of the code to an
        appropriate person or persons identified in the code; and

        (5) Accountability for adherence to the code.

(c) The registrant must briefly describe the nature of any amendment, during the
period covered by the report, to a provision of its code of ethics that applies
to the registrant's principal executive officer, principal financial officer,
principal accounting officer or controller, or persons performing similar
functions, regardless of whether these individuals are employed by the
registrant or a third party, and that relates to any element of the code of
ethics definition enumerated in paragraph (b) of this Item. The registrant must
file a copy of any such amendment as an exhibit pursuant to Item 10(a), unless
the registrant has elected to satisfy paragraph (f) of this Item by posting its
code of ethics on its website pursuant to paragraph (f)(2) of this Item, or by
undertaking to provide its code of ethics to any person without charge, upon
request, pursuant to paragraph (f)(3) of this Item.

The registrant has made no amendments to the code of ethics during the period
covered by this report.

(d) If the registrant has, during the period covered by the report, granted a
waiver, including an implicit waiver, from a provision of the code of ethics to
the registrant's principal executive officer, principal financial officer,
principal accounting officer or controller, or persons performing similar
functions, regardless of whether these individuals are employed by the
registrant or a third party, that relates to one or more of the items set forth
in paragraph (b) of this Item, the registrant must briefly describe the nature
of the waiver, the name of the person to whom the waiver was granted, and the
date of the waiver.

Not applicable.

(e) If the registrant intends to satisfy the disclosure requirement under
paragraph (c) or (d) of this Item regarding an amendment to, or a waiver from,
a provision of its code of ethics that applies to the registrant's principal
executive officer, principal financial officer, principal accounting officer or
controller, or persons performing similar functions and that relates to any
element of the code of ethics definition enumerated in paragraph (b) of this
Item by posting such information on its Internet website, disclose the
registrant's Internet address and such intention.

Not applicable.

(f) The registrant must:

        (1) File with the Commission, pursuant to Item 10(a), a copy of its code
        of ethics that applies to the registrant's principal executive officer,
        principal financial officer, principal accounting officer or controller,
        or persons performing similar functions, as an exhibit to its annual
        report on this Form N-CSR (see attachment);

        (2) Post the text of such code of ethics on its Internet website and
        disclose, in its most recent report on this Form N-CSR, its Internet
        address and the fact that it has posted such code of ethics on its
        Internet website; or

        (3) Undertake in its most recent report on this Form N-CSR to provide to
        any person without charge, upon request, a copy of such code of ethics
        and explain the manner in which such request may be made.
	See Item 10(2)

ITEM 3. AUDIT COMMITTEE FINANCIAL EXPERT.

(a) (1)  Disclose that the registrant's board of trustees has determined that
         the registrant either:

    (i)  Has at least one audit committee financial expert serving on its audit
         committee; or

    (ii) Does not have an audit committee financial expert serving on its audit
         committee.

The registrant's Board of Trustees has determined that the registrant has at
least one audit committee financial expert.

    (2) If the registrant provides the disclosure required by paragraph
(a)(1)(i) of this Item, it must disclose the name of the audit committee
financial expert and whether that person is "independent." In order to be
considered "independent" for purposes of this Item, a member of an audit
committee may not, other than in his or her capacity as a member of the audit
committee, the board of trustees, or any other board committee:

    (i)  Accept directly or indirectly any consulting, advisory, or other
         compensatory fee from the issuer; or

    (ii) Be an "interested person" of the investment company as defined in
         Section 2(a)(19) of the Act (15 U.S.C. 80a-2(a)(19)).

Ms. Marguerite A. Piret, an independent trustee, is such an audit committee
financial expert.

    (3) If the registrant provides the disclosure required by paragraph (a)(1)
(ii) of this Item, it must explain why it does not have an audit committee
financial expert.

Not applicable.


ITEM 4. PRINCIPAL ACCOUNTANT FEES AND SERVICES.

(a) Disclose, under the caption AUDIT FEES, the aggregate fees billed for each
of the last two fiscal years for professional services rendered by the principal
accountant for the audit of the registrant's annual financial statements or
services that are normally provided by the accountant in connection with
statutory and regulatory filings or engagements for those fiscal years.

N/A

(b) Disclose, under the caption AUDIT-RELATED FEES, the aggregate fees billed in
each of the last two fiscal years for assurance and related services by the
principal accountant that are reasonably related to the performance of the audit
of the registrant's financial statements and are not reported under
paragraph (a) of this Item. Registrants shall describe the nature of the
services comprising the fees disclosed under this category.

N/A

(c) Disclose, under the caption TAX FEES, the aggregate fees billed in each of
the last two fiscal years for professional services rendered by the principal
accountant for tax compliance, tax advice, and tax planning. Registrants shall
describe the nature of the services comprising the fees disclosed under this
category.

N/A

(d) Disclose, under the caption ALL OTHER FEES, the aggregate fees billed in
each of the last two fiscal years for products and services provided by the
principal accountant, other than the services reported in paragraphs (a) through
(c) of this Item. Registrants shall describe the nature of the services
comprising the fees disclosed under this category.

N/A

(e) (1) Disclose the audit committee's pre-approval policies and procedures
described in paragraph (c)(7) of Rule 2-01 of Regulation S-X.

 PIONEER FUNDS
            APPROVAL OF AUDIT, AUDIT-RELATED, TAX AND OTHER SERVICES
                       PROVIDED BY THE INDEPENDENT AUDITOR

                  SECTION I - POLICY PURPOSE AND APPLICABILITY

The Pioneer Funds recognize the importance of maintaining the independence of
their outside auditors. Maintaining independence is a shared responsibility
involving Pioneer Investment Management, Inc ("PIM"), the audit committee and
the independent auditors.

The Funds recognize that a Fund's independent auditors: 1) possess knowledge of
the Funds, 2) are able to incorporate certain services into the scope of the
audit, thereby avoiding redundant work, cost and disruption of Fund personnel
and processes, and 3) have expertise that has value to the Funds. As a result,
there are situations where it is desirable to use the Fund's independent
auditors for services in addition to the annual audit and where the potential
for conflicts of interests are minimal. Consequently, this policy, which is
intended to comply with Rule 210.2-01(C)(7), sets forth guidelines and
procedures to be followed by the Funds when retaining the independent audit firm
to perform audit, audit-related tax and other services under those
circumstances, while also maintaining independence.

Approval of a service in accordance with this policy for a Fund shall also
constitute approval for any other Fund whose pre-approval is required pursuant
to Rule 210.2-01(c)(7)(ii).

In addition to the procedures set forth in this policy, any non-audit services
that may be provided consistently with Rule 210.2-01 may be approved by the
Audit Committee itself and any pre-approval that may be waived in accordance
with Rule 210.2-01(c)(7)(i)(C) is hereby waived.

Selection of a Fund's independent auditors and their compensation shall be
determined by the Audit Committee and shall not be subject to this policy.



                               SECTION II - POLICY

---------------- -------------------------------- -------------------------------------------------
SERVICE           SERVICE CATEGORY DESCRIPTION      SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
CATEGORY
---------------- -------------------------------- -------------------------------------------------
                                            
I.  AUDIT        Services that are directly       o Accounting research assistance
SERVICES         related to performing the        o SEC consultation, registration
                 independent audit of the Funds     statements, and reporting
                                                  o Tax accrual related matters
                                                  o Implementation of new accounting
                                                    standards
                                                  o Compliance letters (e.g. rating agency
                                                    letters)
                                                  o Regulatory reviews and assistance
                                                    regarding financial matters
                                                  o Semi-annual reviews (if requested)
                                                  o Comfort letters for closed end
                                                    offerings
---------------- -------------------------------- -------------------------------------------------
II.              Services which are not           o AICPA attest and agreed-upon procedures
AUDIT-RELATED    prohibited under Rule            o Technology control assessments
SERVICES         210.2-01(C)(4) (the "Rule")      o Financial reporting control assessments
                 and are related extensions of    o Enterprise security architecture
                 the audit services support the     assessment
                 audit, or use the
                 knowledge/expertise gained
                 from the audit procedures as a
                 foundation to complete the
                 project.  In most cases, if
                 the Audit-Related Services are
                 not performed by the Audit
                 firm, the scope of the Audit
                 Services would likely
                 increase.  The Services are
                 typically well-defined and
                 governed by accounting
                 professional standards (AICPA,
                 SEC, etc.)
---------------- -------------------------------- -------------------------------------------------

 ------------------------------------- ------------------------------------
                                    
   AUDIT COMMITTEE APPROVAL POLICY               AUDIT COMMITTEE
                                                REPORTING POLICY
 ------------------------------------- ------------------------------------
                                    
 o "One-time" pre-approval             o A summary of all such
   for the audit period for all          services and related fees
   pre-approved specific service         reported at each regularly
   subcategories.  Approval of the       scheduled Audit Committee
   independent auditors as               meeting.
   auditors for a Fund shall
   constitute pre approval for
   these services.
 ------------------------------------- ------------------------------------
 o "One-time" pre-approval             o A summary of all such
   for the fund fiscal year within       services and related fees
   a specified dollar limit              (including comparison to
   for all pre-approved                  specified dollar limits)
   specific service subcategories        reported quarterly.

 o Specific approval is
   needed to exceed the
   pre-approved dollar limit for
   these services (see general
   Audit Committee approval policy
   below for details on obtaining
   specific approvals)

 o Specific approval is
   needed to use the Fund's
   auditors for Audit-Related
   Services not denoted as
   "pre-approved", or
   to add a specific service
   subcategory as "pre-approved"
 ------------------------------------- ------------------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- --------------------------- -----------------------------------------------
   SERVICE CATEGORY          SERVICE CATEGORY        SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
                               DESCRIPTION
----------------------- --------------------------- -----------------------------------------------
                                              
III. TAX SERVICES       Services which are not      o Tax planning and support
                        prohibited by the Rule,     o Tax controversy assistance
                        if an officer of the Fund   o Tax compliance, tax returns, excise
                        determines that using the     tax returns and support
                        Fund's auditor to provide   o Tax opinions
                        these services creates
                        significant synergy in
                        the form of efficiency,
                        minimized disruption, or
                        the ability to maintain a
                        desired level of
                        confidentiality.
----------------------- --------------------------- -----------------------------------------------

------------------------------------- -------------------------
  AUDIT COMMITTEE APPROVAL POLICY         AUDIT COMMITTEE
                                          REPORTING POLICY
------------------------------------- -------------------------
------------------------------------- -------------------------
o "One-time" pre-approval             o A summary of
  for the fund fiscal  year             all such services and
  within a specified dollar limit       related fees
  				        (including comparison
  			                to specified dollar
  			                limits) reported
  			                quarterly.

o Specific approval is
  needed to exceed the
  pre-approved dollar limits for
  these services (see general
  Audit Committee approval policy
  below for details on obtaining
  specific approvals)

o Specific approval is
  needed to use the Fund's
  auditors for tax services not
  denoted as pre-approved, or to add a specific
  service subcategory as
  "pre-approved"
------------------------------------- -------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- --------------------------- -----------------------------------------------
   SERVICE CATEGORY          SERVICE CATEGORY        SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
                               DESCRIPTION
----------------------- --------------------------- -----------------------------------------------
                                              
IV.  OTHER SERVICES     Services which are not      o Business Risk Management support
                        prohibited by the Rule,     o Other control and regulatory
A. SYNERGISTIC,         if an officer of the Fund     compliance projects
UNIQUE QUALIFICATIONS   determines that using the
                        Fund's auditor to provide
                        these services creates
                        significant synergy in
                        the form of efficiency,
                        minimized disruption,
                        the ability to maintain a
                        desired level of
                        confidentiality, or where
                        the Fund's auditors
                        posses unique or superior
                        qualifications to provide
                        these services, resulting
                        in superior value and
                        results for the Fund.
----------------------- --------------------------- -----------------------------------------------

--------------------------------------- ------------------------
    AUDIT COMMITTEE APPROVAL POLICY         AUDIT COMMITTEE
                                            REPORTING POLICY
------------------------------------- --------------------------
                                   
o "One-time" pre-approval             o A summary of
  for the fund fiscal year within       all such services and
  a specified dollar limit              related fees
  			               (including comparison
  			                to specified dollar
  				        limits) reported
                                        quarterly.
o Specific approval is
  needed to exceed the
  pre-approved dollar limits for
  these services (see general
  Audit Committee approval policy
  below for details on obtaining
  specific approvals)

o Specific approval is
  needed to use the Fund's
  auditors for "Synergistic" or
  "Unique Qualifications" Other
  Services not denoted as
  pre-approved to the left, or to
  add a specific service
  subcategory as "pre-approved"
------------------------------------- --------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- ------------------------- -----------------------------------------------
   SERVICE CATEGORY         SERVICE CATEGORY        SPECIFIC PROHIBITED SERVICE SUBCATEGORIES
                              DESCRIPTION
----------------------- ------------------------- -----------------------------------------------
                                            
PROHIBITED  SERVICES    Services which result     1. Bookkeeping or other services
                        in the auditors losing       related to the accounting records or
                        independence status          financial statements of the audit
                        under the Rule.              client*
                                                  2. Financial information systems design
                                                     and implementation*
                                                  3. Appraisal or valuation services,
                                                     fairness* opinions, or
                                                     contribution-in-kind reports
                                                  4. Actuarial services (i.e., setting
                                                     actuarial reserves versus actuarial
                                                     audit work)*
                                                  5. Internal audit outsourcing services*
                                                  6. Management functions or human
                                                     resources
                                                  7. Broker or dealer, investment
                                                     advisor, or investment banking services
                                                  8. Legal services and expert services
                                                     unrelated to the audit
                                                  9. Any other service that the Public
                                                     Company Accounting Oversight Board
                                                     determines, by regulation, is
                                                     impermissible
----------------------- ------------------------- -----------------------------------------------

------------------------------------------- ------------------------------
     AUDIT COMMITTEE APPROVAL POLICY               AUDIT COMMITTEE
                                                  REPORTING POLICY
------------------------------------------- ------------------------------
o These services are not to be              o A summary of all
  performed with the exception of the(*)      services and related
  services that may be permitted              fees reported at each
  if they would not be subject to audit       regularly scheduled
  procedures at the audit client (as          Audit Committee meeting
  defined in rule 2-01(f)(4)) level           will serve as continual
  the firm providing the service.             confirmation that has
  				              not provided any
                                              restricted services.
------------------------------------------- ------------------------------

--------------------------------------------------------------------------------
GENERAL AUDIT COMMITTEE APPROVAL POLICY:
o For all projects, the officers of the Funds and the Fund's auditors will each
  make an assessment to determine that any proposed projects will not impair
  independence.

o Potential services will be classified into the four non-restricted service
  categories and the "Approval of Audit, Audit-Related, Tax and Other
  Services" Policy above will be applied. Any services outside the specific
  pre-approved service subcategories set forth above must be specifically
  approved by the Audit Committee.

o At least quarterly, the Audit Committee shall review a report summarizing the
  services by service category, including fees, provided by the Audit firm as
  set forth in the above policy.

--------------------------------------------------------------------------------


    (2) Disclose the percentage of services described in each of paragraphs (b)
   through (d) of this Item that were approved by the audit committee pursuant
   to paragraph (c)(7)(i)(C) of Rule 2-01 of Regulation S-X.

N/A

(f) If greater than 50 percent, disclose the percentage of hours expended on the
principal accountant's engagement to audit the registrant's financial statements
for the most recent fiscal year that were attributed to work performed by
persons other than the principal accountant's full-time, permanent employees.

N/A

(g) Disclose the aggregate non-audit fees billed by the registrant's accountant
for services rendered to the registrant, and rendered to the registrant's
investment adviser (not including any sub-adviser whose role is primarily
portfolio management and is subcontracted with or overseen by another investment
adviser), and any entity controlling, controlled by, or under common control
with the adviser that provides ongoing services to the registrant for each of
the last two fiscal years of the registrant.

N/A

(h) Disclose whether the registrant's audit committee of the board of trustees
has considered whether the provision of non-audit services that were rendered to
the registrant's investment adviser (not including any subadviser whose role is
primarily portfolio management and is subcontracted with or overseen by another
investment adviser), and any entity controlling, controlled by, or under common
control with the investment adviser that provides ongoing services to the
registrant that were not pre-approved pursuant to paragraph (c)(7)(ii) of
Rule 2-01 of Regulation S-X is compatible with maintaining the principal
accountant's independence.

The Fund's audit committee of the Board of Trustees has
considered whether the provision of non-audit services that
were rendered to the Affiliates (as defined) that were not pre-
approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of
Regulation S-X is compatible with maintaining the principal
accountant's independence.

Item 5. Audit Committee of Listed Registrants

(a) If the registrant is a listed issuer as defined in Rule 10A-3
under the Exchange Act (17 CFR 240.10A-3), state whether
or not the registrant has a separately-designated standing
 audit committee established in accordance with Section
3(a)(58)(A) of the Exchange Act (15 U.S.C. 78c(a)(58)(A)).
If the registrant has such a committee, however designated,
identify each committee member. If the entire board of directors
is acting as the registrants audit committee as specified in
Section 3(a)(58)(B) of the Exchange Act (15 U.S.C. 78c(a)(58)(B)),
so state.

The registrant has a separately-designated standing audit
committe eestablished in accordance with Section
3(a)(58)(A) of the Exchange Act (15 U.S.C. 78c(a)(58)(A)).

(b) If applicable, provide the disclosure required by Rule 10A-3(d)
under the Exchange Act (17 CFR 240.10A-3(d)) regarding an exemption
from the listing standards for audit committees.

N/A

Item 6. Schedule of Investments.

File Schedule I Investments in securities of unaffiliated issuers
as of the close of the reporting period as set forth in 210.12-
12 of Regulation S-X [17 CFR 210.12-12], unless the schedule is
included as part of the report to shareholders filed under Item
1 of this Form.

Included in Item 1


ITEM 7. DISCLOSURE OF PROXY VOTING POLICIES AND PROCEDURES FOR
CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

A closed-end management investment company that is filing an annual report on
this Form N-CSR must, unless it invests exclusively in non-voting securities,
describe the policies and procedures that it uses to determine how to vote
proxies relating to portfolio securities, including the procedures that the
company uses when a vote presents a conflict between the interests of its
shareholders, on the one hand, and those of the company's investment adviser;
principal underwriter; or any affiliated person (as defined in Section 2(a)(3)
of the Investment Company Act of 1940 (15 U.S.C. 80a-2(a)(3)) and the rules
thereunder) of the company, its investment adviser, or its principal
underwriter, on the other. Include any policies and procedures of the company's
investment adviser, or any other third party, that the company uses, or that are
used on the company's behalf, to determine how to vote proxies relating to
portfolio securities.

Information not required in semi annual reports on form NCSR.

Item 8. Portfolio Managers of Closed-End Management Investment
        Companies.

(a) If the registrant is a closed-end management investment company that
is filing an annual report on this Form N-CSR,provide the following
information:
(1) State the name, title, and length of service of the person or persons
employed by or associated with the registrant or an investment adviser
of the registrant who are primarily responsible for the day-to-day management
of the registrants portfolio (Portfolio Manager). Also state each Portfolio
Managers business experience during the past 5 years.

Information not required in semi annual reports on form NCSR.

Item 9. Purchases of Equity Securities by Closed-End Management
Investment Company and Affiliated Purchasers.

(a) If the registrant is a closed-end management investment company,
in the following tabular format, provide the information specified in
paragraph (b) of this Item with respect to any purchase made by or on
behalf of the registrant or any affiliated purchaser, as defined in
Rule 10b-18(a)(3) under the Exchange Act (17 CFR 240.10b-18(a)(3)), of
shares or other units of any class of the registrants equity securities
that is registered by the registrant pursuant to Section 12 of the
Exchange Act (15 U.S.C. 781). Instruction to paragraph (a). Disclose
all purchases covered by this Item, including purchases that do not
satisfy the conditions of the safe harbor of Rule 10b-18 under the
Exchange Act (17 CFR 240.10b-18), made in the period covered by the
report. Provide disclosures covering repurchases made on a monthly basis.
For example, if the reporting period began on January 16 and ended on
July 15, the chart would show repurchases for the months from January 16
through February 15, February 16 through March 15, March 16 through
April 15, April 16 through May 15, May 16 through June 15, and June 16
through July 15.

During the period covered by this report, there were no purchases
made by or on behalf of the registrant or any affiliated purchaser
as defined in Rule 10b-18(a)(3) under the Securities Exchange Act
of 1934 (the Exchange Act), of shares of the registrants equity
securities that are registered by the registrant pursuant to
Section 12 of the Exchange Act.


Item 10. Submission of Matters to a Vote of Security Holders.

Describe any material changes to the procedures by which shareholders
may recommend nominees to the registrants board of directors, where
those changes were implemented after the registrant last provided
disclosure in response to the requirements of Item 7(d)(2)(ii)(G)
of Schedule 14A (17 CFR 240.14a-101), or this Item.


There have been no material changes to the procedures by which the
shareholders may recommend nominees to the registrants board of
directors since the registrant last provided disclosure in response
to the requirements of Item 7(d)(2)(ii)(G) of Schedule 14(A) in
its definitive proxy statement, or this Item.


ITEM 11. CONTROLS AND PROCEDURES.

(a) Disclose the conclusions of the registrant's principal executive officer or
officers and principal financial officer or officers, or persons performing
similar functions, about the effectiveness of the registrant's disclosure
controls and procedures (as defined in Rule 30a-2(c) under the Act (17 CFR
270.30a-2(c))) based on their evaluation of these controls and procedures as of
a date within 90 days of the filing date of the report that includes the
disclosure required by this paragraph.

The registrant's principal executive officer
and principal financial officer have
concluded that the registrant's disclosure
controls and procedures are effective based
on their evaluation of these controls and
procedures as of a date within 90 days of the
filing date of this report.


(b) Disclose whether or not there were significant changes in the registrant's
internal controls or in other factors that could significantly affect these
controls subsequent to the date of their evaluation, including any corrective
actions with regard to significant deficiencies and material weaknesses.

There were no significant changes in the
registrant's internal control over financial
reporting that occurred during the second
fiscal quarter of the period covered by this
report that have materially affected, or are
reasonably likely to materially affect, the
registrant's internal control over financial
reporting.

The registrant's principal executive officer and principal financial
officer, however, voluntarily are reporting the following information:

In August of 2006 the registrant's investment adviser
enhanced its internal procedures for reporting performance
information required to be included in prospectuses.
Those enhancements involved additional internal controls
over the appropriateness of performance data
generated for this purpose.  Such enhancements were made
following an internal review which identified
prospectuses relating to certain classes of shares of
a limited number of registrants where, inadvertently,
performance information not reflecting the deduction of
applicable sales charges was included. Those prospectuses
were revised, and the revised prospectuses were distributed to
shareholders.


ITEM 12. EXHIBITS.

File the exhibits listed below as part of this Form. Letter or number the
exhibits in the sequence indicated.

(a) Any code of ethics, or amendment thereto, that is the subject of the
disclosure required by Item 2, to the extent that the registrant intends to
satisfy the Item 2 requirements through filing of an exhibit.



(b) A separate certification for each principal executive officer and principal
financial officer of the registrant as required by Rule 30a-2 under the Act
(17 CFR 270.30a-2).

Filed herewith.





                                   SIGNATURES

                          [See General Instruction F]


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, the registrant has duly caused this report to be
signed on its behalf by the undersigned, thereunto duly authorized.


(Registrant) Pioneer Municipal High Income Advantage Trust


By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr, President

Date November 29, 2012


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on the
dates indicated.


By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr., President

Date November 29, 2012


By (Signature and Title)* /s/ Mark Bradley
Mark Bradley, Treasurer & Chief Accounting & Financial Officer

Date November 29, 2012

* Print the name and title of each signing officer under his or her signature.