FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * SCHRODER VENTURE MANAGERS LTD   2. Issuer Name and Ticker or Trading Symbol Solexa, Inc. [SLXA] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 22 CHURCH STREET,  3. Date of Earliest Transaction (Month/Day/Year) 04/21/2005 (Street) HAMILTON HM 11 BERMUDA, D0 0 4. If Amendment, Date Original Filed(Month/Day/Year) 04/25/2005 6. Individual or Joint/Group Filing(Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/21/2005   (1)(20) P   330,730 A (16) 2,119,495 I See Footnote (2) (8) Common Stock 04/21/2005   (1)(20) P   140,857 A (16) 902,683 I See Footnote (3) (8) Common Stock 04/21/2005   (1)(20) P   37,538 A (16) 240,560 I See Footnote (4) (8) Common Stock 04/21/2005   (1)(20) P   9,511 A (16) 60,952 I See Footnote (5) (8) Common Stock 04/21/2005   (1)(20) P   40,736 A (16) 261,056 I See Footnote (6) (8) Common Stock 04/21/2005   (1)(20) P   5,102 A (16) 32,698 I See Footnote (7) (8)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		165,365		(18)	(19)	Common Stock	165,365	(17)	165,365	I	See Footnote (9) (15)
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		70,428		(18)	(19)	Common Stock	70,428	(17)	70,428	I	See Footnote (10) (15)
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		18,769		(18)	(19)	Common Stock	18,769	(17)	18,769	I	See Footnote (11) (15)
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		4,756		(18)	(19)	Common Stock	4,756	(17)	4,756	I	See Footnote (12) (15)
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		20,368		(18)	(19)	Common Stock	20,368	(17)	20,368	I	See Footnote (13) (15)
Warrant (right to buy)	$ 5	04/21/2005	(1)(20)	P		2,551		(18)	(19)	Common Stock	2,551	(17)	2,551	I	See Footnote (14) (15)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
SCHRODER VENTURE MANAGERS LTD 22 CHURCH STREET HAMILTON HM 11 BERMUDA, D0 0		X
SITCO Nominees Ltd. VC 01903 as Nominee of Schroder Ventures International Life Sciences Fund II Group Co-Investment Scheme C/O GOODWIN PROCTER 53 STATE STREET BOSTON, MA 02109		X
Schroder Ventures International Life Sciences Fund II Strategic Partners L.P. C/O GOODWIN PROCTER 53 STATE STREET BOSTON, MA 02109		X
Schroder Ventures International Life Sciences Fund II L.P.3 C/O GOODWIN PROCTER 53 STATE STREET BOSTON, MA 02109		X
Schroder Ventures International Life Sciences Fund II L.P.2 C/O GOODWIN PROCTER 53 STATE STREET BOSTON, MA 02109		X
SV (Nominees) LTD as Nominee of Schroder Ventures Investments LTD C/O GOODWIN PROCTER 53 STATE STREET BOSTON, MA 02109		X
SCHRODER VENTURES MANAGERS INC 787 SEVENTH AVENUE 29TH FLOOR NEW YORK, NY 10019		X
SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II LP1 787 SEVENTH AVENUE 34TH FLOOR NEW YORK, NY 10019		X

Signatures

/s/ Gary Carr /s/ Douglas Mello		04/27/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	On April 21, 2005, Schroder Ventures International Life Sciences Fund II L.P.1 ("ILSF LP1"), Schroder Ventures International Life Sciences Fund II L.P.2 ("ILSF LP2"), Schroder Ventures International Life Sciences Fund II L.P.3 ("ILSF LP3"), SITCO Nominees Ltd. -- VC 01903 as Nominee for Schroder Ventures International Life Sciences Fund II Group Co-Investment Scheme ("Co-Invest"), SV (Nominees) Limited as Nominee for Schroder Ventures Investments Limited ("SVIL") and Schroder Ventures International Life Sciences Fund II Strategic Partners L.P. ("Strategic Partners") (each a "Fund", or collectively the "Funds") entered into a Securities Purchase Agreement (the "Agreement") with Solexa, Inc. (the "Company") pursuant to which the Funds will acquire shares of Company common stock and warrants for the purchase of Company common stock, subject to the approval of the transaction by the Company's shareholders and the satisfaction of certain other conditions outlined in the Agreement.
(2)	These shares will be owned directly by ILSF LP1. Schroder Venture Managers Inc. ("SVMI"), the general partner of ILSF LP1, and Schroder Venture Managers Limited ("SVML"), investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP1 except to the extent of any pecuniary interest therein.
(3)	These shares will be owned directly by ILSF LP2. SVMI, the general partner of ILSF LP2, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP2 except to the extent of any pecuniary interest therein.
(4)	These shares will be owned directly by ILSF LP3. SVMI, the general partner of ILSF LP3, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by ILSF LP3. SVMI and SVML disclaim beneficial ownership of shares held by ILSF LP3 except to the extent of any pecuniary interest therein.
(5)	These shares will be owned directly by Co-Invest. SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by Co-Invest because of a contractual relationship between Co-Invest and SVMI. SVMI and SVML disclaim beneficial ownership of shares held by Co-Invest except to the extent of any pecuniary interest therein.
(6)	These shares will be owned directly by SVIL. SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by SVIL because of a contractual relationship between SVIL and SVMI. SVMI and SVML disclaim beneficial ownership of shares held by SVIL except to the extent of any pecuniary interest therein.
(7)	These shares will be owned directly by Strategic Partners. SVMI, the general partner of Strategic Partners, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the shares held by Strategic Partners. SVMI and SVML disclaim beneficial ownership of shares held by Strategic Partners except to the extent of any pecuniary interest therein.
(8)	Each Fund may be deemed to beneficially own the shares held by the Funds because of certain contractual relationships among the Funds and their affiliates. The Funds disclaim beneficial ownership of shares held by any Fund except to the extent of any pecuniary interest therein.
(9)	These warrants will be owned directly by ILSF LP1. SVMI, the general partner of ILSF LP1, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1 except to the extent of any pecuniary interest therein.
(10)	These warrants will be owned directly by ILSF LP2. SVMI, the general partner of ILSF LP2, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP1. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP2 except to the extent of any pecuniary interest therein.
(11)	These warrants will be owned directly by ILSF LP3. SVMI, the general partner of ILSF LP3, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP3. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by ILSF LP3 except to the extent of any pecuniary interest therein.
(12)	These warrants will be owned directly by Co-Invest. SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Co-Invest because of a contractual relationship between Co-Invest and SVMI. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Co-Invest except to the extent of any pecuniary interest therein.
(13)	These warrants will be owned directly by SVIL. SVMI and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by SVIL because of a contractual relationship between SVIL and SVMI. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by SVIL except to the extent of any pecuniary interest therein.
(14)	These warrants will be owned directly by Strategic Partners. SVMI, the general partner of Strategic Partners, and SVML, investment manager to SVMI, may be deemed to share voting and dispositive power over the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Strategic Partners. SVMI and SVML disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by Strategic Partners except to the extent of any pecuniary interest therein.
(15)	Each Fund may be deemed to beneficially own the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by the Funds because of certain contractual relationships among the Funds and their affiliates. The Funds disclaim beneficial ownership of the warrants (and the underlying shares of common stock in the event such warrants were exercised) held by any Fund except to the extent of any pecuniary interest therein.
(16)	Under the terms of the Agreement, these shares of Common Stock will be acquired for approximately $4.00 per share.
(17)	An unspecified percentage of the total consideration paid by the Funds under the Agreement will represent consideration for the Warrants.
(18)	The Warrants may be exercised at the election of the holder one hundred and eighty (180) days after the date of issuance.
(19)	The Warrants will expire five (5) years after the date of issuance.
(20)	This filing amends a Form 4 filed on April 25, 2005 and is intended to clarify the numerous conditions precedent, namely shareholder approval of the transaction, to the consummation of the described acquisitions.

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