SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                 SCHEDULE 13D/A
                                 (Rule 13d-101)

                  Under the Securities and Exchange Act of 1934
                                (Amendment No. 1)

                                  E-Z-EM, INC.
                                (Name of Issuer)

                                  Common Stock
                         (Title of Class of Securities)

                                   269305 40 5
                                 (CUSIP Number)

                              Scott M. Tayne, Esq.
                       Davies Ward Phillips & Vineberg LLP
                 625 Madison Ave, 12th Floor, New York, NY 10022
                                 (212) 308-8866
                       (Name, Address and Telephone Number
           of Person Authorized to Receive Notices and Communications)

                                 April 27, 2005
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  that is the subject of this  Schedule  13D, and is filing this
schedule  because of Rule 13d-1(e),  Rule 13d-1(f) or Rule  13d-1(g),  check the
following box. |_|

Note:  Schedules  filed in paper format shall include a signed original and five
copies of the  schedule,  including  all  exhibits.  See Rule 13d-7(b) for other
parties to whom copies are to be sent.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).




--------------------------------------------------------------------------------
1    NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSON

     Howard S. Stern
--------------------------------------------------------------------------------
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a)  |_| 
                                                                 (b)  |_| 
--------------------------------------------------------------------------------
3    SEC USE ONLY


--------------------------------------------------------------------------------
4    SOURCE OF FUNDS*

     N/A
--------------------------------------------------------------------------------
5    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
     PURSUANT TO ITEMS 2(d) OR 2(e)                                   |_| 


--------------------------------------------------------------------------------
6    CITIZENSHIP OR PLACE OF ORGANIZATION

     United States
--------------------------------------------------------------------------------
               7    SOLE VOTING POWER
                    
                    2,027,974
               -----------------------------------------------------------------
  NUMBER OF    8    SHARED VOTING POWER
   SHARES           
BENEFICIALLY        0
  OWNED BY     -----------------------------------------------------------------
    EACH       9    SOLE DISPOSITIVE POWER
  REPORTING         
   PERSON           2,027,974
    WITH       -----------------------------------------------------------------
               10   SHARED DISPOSITIVE POWER
                    
                    0
--------------------------------------------------------------------------------
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON


--------------------------------------------------------------------------------
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     18.8%
--------------------------------------------------------------------------------
14   TYPE OF REPORTING PERSON*

     IN
--------------------------------------------------------------------------------
                     *SEE INSTRUCTIONS BEFORE FILLING OUT!


                                       2


Introduction

      This  Amendment  No.  1 to  Schedule  13D  amends  the  Schedule  13D (the
"Schedule")  filed  jointly on September 29, 2003 by Howard S. Stern ("HSS") and
certain  members of his family  (each a  "reporting  person"  and  together  the
"reporting  persons")  relating to their acquisition of beneficial  ownership of
shares of common  stock,  par value  $.10 per share  (the  "Common  Stock"),  of
E-Z-EM,  Inc. ("E-Z-EM") pursuant to a reclassification by E-Z-EM of its Class A
(voting) common stock and Class B (nonvoting) common stock into the Common Stock
(the  "Reclassification")  in October 2002. The reporting  persons jointly filed
the  Schedule  because each  reporting  person had,  with  certain  other E-Z-EM
stockholders  and E-Z-EM,  entered into a stockholders'  agreement,  dated as of
July 15, 2002, (the  "Stockholders'  Agreement"),  that  pertained,  among other
things, to the voting and disposition of the parties' shares of E-Z-EM's capital
stock, including an agreement to vote in favor of the Reclassification.

      Upon  completion  of the  Reclassification  in  October  2002,  all of the
obligations between and among the parties to the Stockholders'  Agreement either
were fully performed or had expired,  except for certain  agreements,  in effect
until  July 15,  2004,  not to  submit,  or vote in favor  of,  any  stockholder
proposals  similar  in nature to those  submitted  to E-Z-EM  (and  subsequently
withdrawn) by certain of the parties for inclusion in the E-Z-EM proxy statement
for the 2002 annual meeting of E-Z-EM stockholders.

Item 4. Purpose of Transaction

      Item 4 of the  Schedule is hereby  amended by adding the  following at the
      end thereof:

      On April 27, 2005, HSS entered into a stock trading plan for E-Z-EM Common
      Stock with Fidelity Brokerage Services, LLC ("Fidelity"). The trading plan
      is intended to comply with the  requirements  of Rule 10b5-1(c)  under the
      Securities  Exchange Act of 1934.  The trading plan,  which  terminates on
      December 31, 2005,  provides for sales of a specified  number of shares of
      E-Z-EM  Common Stock each week during the term of the plan,  commencing in
      the  first  week of May,  2005.  HSS has  adopted  the  trading  plan  for
      diversification  and liquidity  purposes.  HSS may modify the trading plan
      from time to time or terminate the plan in accordance with its terms.

      To comply with the private  letter  ruling (the "PLR")  obtained by E-Z-EM
      from the Internal Revenue Service in connection with E-Z-EM's  spin-off of
      AngioDynamics,  Inc.  ("AngioDynamics")  to  the  E-Z-EM  stockholders  in
      October,  2004,  all  sales  of  E-Z-EM  Common  Stock by HSS must be made
      concurrently with sales of a proportional number of shares of common stock
      of AngioDynamics. In connection therewith, HSS has previously entered into
      a Rule 10b5-1(c) trading plan for sales of AngioDynamics common stock.

      In  addition,  HSS  expects  to  evaluate  on an  ongoing  basis  E-Z-EM's
      financial condition,  business operations and prospects,  the market price
      of the E-Z-EM Common Stock,  conditions in securities  markets  generally,
      general economic and industry  conditions and other factors.  Accordingly,
      HSS reserves the right to change his plans and  intentions at any time, as
      he deems appropriate.  In particular, HSS may


                                       3


      acquire  additional  shares of E-Z-EM Common Stock,  dispose of additional
      shares of E-Z-EM  Common  Stock  and/or  enter into  privately  negotiated
      derivative  transactions  with  institutional  counterparties to hedge the
      market risk of some or all of its positions in the Common Stock.  However,
      HSS intends to limit his sales of E-Z-EM  Common Stock in each year in the
      two-year  period that commenced on October 30, 2004, to no more than 1% of
      the outstanding shares of E-Z-EM Common Stock, as contemplated in the PLR.
      Any such  transactions  may be  effected at any time and from time to time
      subject to any  applicable  limitations  of the Securities Act of 1933 and
      the rules and regulations promulgated thereunder.

      As of the date of this  Amendment No. 1, HSS has no other plan or proposal
      that  relates to or would  result in any of the actions set forth in parts
      (a) through (j) of Item 4 of Schedule 13D.

Item 5. Interest in Securities of the Issuer.

      The first  paragraph of Item 5(a) of the Schedule is amended by adding the
      following at the end thereof:

      As of the date hereof, HSS  beneficially  owns 2,027,974  shares of E-Z-EM
      Common Stock.  Such shares  represent 18.8% of the  outstanding  shares of
      E-Z-EM Common Stock.  These shares  include 29,475 shares subject to stock
      options that are currently  exercisable,  or that will become  exercisable
      within 60 days,  at exercise  prices of $5.8222 per share (1,825  shares),
      $5.434 per share (1,825  shares),  $12.66 per share (24,000  shares),  and
      $12.0971  per  share  (1,825  shares).  The  options  held  by HSS  for an
      aggregate of 5,475 shares were initially  exercisable  for an aggregate of
      6,000 shares at higher exercise prices. In connection with the spin-off by
      E-Z-EM of  AngioDynamics on October 30, 2004, the number of shares subject
      to the options  was  reduced to their  current  number,  and the  exercise
      prices of the options  were  reduced by  approximately  35%, to  maintain,
      together with options for  AngioDynamics  common stock granted to HSS, the
      economic value of his E-Z-EM options before the spin-off.

      The first paragraph of Item 5(b) of the Schedule is  amended by adding the
      following at the end thereof:

      HSS has the sole voting and dispositive  rights with respect to the shares
      of E-Z-EM Common Stock that he owns.

      Item 5(c) of the  Schedule is amended by adding the  following  at the end
      thereof:

      During  the sixty  days  preceding  the date  hereof,  there  have been no
      transactions in the E-Z-EM Common Stock effected by HSS.

Item 6. Contracts, Arrangements, Understandings or Relationships With Respect to
        Securities of the Issuer.

      Item 6 of the Schedule is amended by adding the following paragraph at the
      end thereof:


                                       4


      In connection with the spin-off by E-Z-EM of  AngioDynamics on October 30,
      2004,  the number of shares  subject to, and the  exercise  prices of, all
      outstanding  options to acquire  E-Z-EM  common  stock  were  adjusted  to
      maintain,  together  with options to purchase  AngioDynamics  common stock
      granted to the option  holders,  the economic  value of the E-Z-EM options
      prior to the spin-off.  As a result,  outstanding options for 6,000 shares
      of E-Z-EM Common Stock held by HSS were reduced to 5,475  shares,  and the
      exercise prices  reduced,  as described in amended Item 5(a), as set forth
      above, and incorporated by reference into this Item 6.

      As of  July  15,  2004,  all of the  obligations  of  the  parties  to the
      Stockholders' Agreement, including HSS, had either been fully performed or
      had  terminated.  There  currently are no other  contracts,  arrangements,
      understandings,  or relationships with respect to the securities of E-Z-EM
      between HSS and any other  person,  and HSS  disclaims  membership  in any
      "group"  within the meaning of Section  13(d)(1) of the Exchange  Act, and
      Rule 13d-5(b) thereunder, with respect to the securities of E-Z-EM.

      The Rule  10b5-1  trading  plan  adopted by HSS on April 27,  2005,  which
      terminates  on December 31, 2005,  provides that HSS will sell a specified
      number of shares of E-Z-EM  Common  Stock each week during the term of the
      plan, commencing in the first week of May, 2005.

Item 7. Material to be Filed as Exhibits.

      10.1  E-Z-EM,  Inc.  1984  Directors  and  Consultants  Stock  Option Plan
            (incorporated  by  reference  to  Exhibit  10(b) to  E-Z-EM,  Inc.'s
            Quarterly  Report  on Form  10-Q  for  the  quarterly  period  ended
            December 2, 1995, filed under Commission file number 0-13003.)

      10.2  Form of Stock Option  Agreement for the E-Z-EM,  Inc. 1984 Directors
            and Consultants Stock Option Plan.

      10.3  E-Z-EM,  Inc. 2004 Stock and Incentive Award Plan  (incorporated  by
            reference  to  Exhibit  99.2  to  the  Definitive  Additional  Proxy
            Materials  filed by E-Z-EM,  Inc. with the  Securities  and Exchange
            Commission on October 25, 2004).

      10.4  Form of Stock Option  Agreement for the E-Z-EM,  Inc. 2004 Stock and
            Incentive Award Plan  (incorporated  by reference to Exhibit 10.3 to
            E-Z-EM,  Inc.'s  Quarterly  Report  on Form  10-Q for the  quarterly
            period ended February 26, 2005.)


                                       5


                                    SIGNATURE

      After reasonable  inquiry and to the best of my knowledge and belief,  the
undersigned hereby certifies that the information contained in this statement is
true, complete and correct.

Date: April 28, 2005.


                                                /s/ Howard S. Stern
                                                --------------------------------
                                                Howard S. Stern


                                       6