PAGE 1 000 A000000 09/30/2012 000 C000000 0001258943 000 D000000 N 000 E000000 NF 000 F000000 Y 000 G000000 Y 000 H000000 N 000 I000000 6.1 000 J000000 U 001 A000000 PIONEER MUNICIPAL HIGH INCOME ADVANTAGE TRUST 001 B000000 811-21409 001 C000000 6177427825 002 A000000 60 STATE STREET 002 B000000 BOSTON 002 C000000 MA 002 D010000 02109 003 000000 N 004 000000 N 005 000000 N 006 000000 N 007 A000000 N 007 B000000 0 007 C010100 1 007 C020100 PIONEER MUNICIPAL HIGH INCOME ADVANTAGE TRUST 007 C030100 N 007 C010200 2 007 C010300 3 007 C010400 4 007 C010500 5 007 C010600 6 007 C010700 7 007 C010800 8 007 C010900 9 007 C011000 10 008 A000001 PIONEER INVESTMENT MANAGEMENT, INC. 008 B000001 A 008 C000001 801-8255 008 D010001 BOSTON 008 D020001 MA 008 D030001 02109 010 A000001 PIONEER INVESTMENT MANAGEMENT, INC. 010 B000001 801-8255 010 C010001 BOSTON 010 C020001 MA 010 C030001 02109 010 A000002 BROWN BROTHERS HARRIMAN & CO. 010 C010002 BOSTON 010 C020002 MA 010 C030002 02109 011 A000001 PIONEER FUNDS DISTRIBUTOR, INC. 011 B000001 8-41256 PAGE 2 011 C010001 BOSTON 011 C020001 MA 011 C030001 02109 011 C040001 1820 011 A000002 UBS INVESTMENT BANK 011 B000002 8-022651 011 C010002 STAMFORD 011 C020002 CT 011 C030002 06901 011 A000003 RBC CAPITAL MARKETS CORP. 011 B000003 8-045411 011 C010003 MINNEAPOLIS 011 C020003 MN 011 C030003 55402 011 C040003 4422 011 A000004 MERRILL LYNCH & CO. 011 B000004 8-7221 011 C010004 NEW YORK 011 C020004 NY 011 C030004 10281 011 C040004 1201 011 A000005 JANNEY MONTGOMERY SCOTT, LLC 011 B000005 8-462 011 C010005 PHILADELPHIA 011 C020005 PA 011 C030005 19103 011 C040005 1675 011 A000006 WACHOVIA CAPITAL MARKETS, LLC 011 B000006 8-99999 011 C010006 RICHMOND 011 C020006 VA 011 C030006 23219 012 A000001 PIONEER INVEST. MGMT. SHAREHOLDER SERV. INC. 012 B000001 85-01359 012 C010001 BOSTON 012 C020001 MA 012 C030001 02109 012 A000002 AMERICAN STOCK TRANSFER & TRUST CO. (COMMON) 012 B000002 85-00000 012 C010002 BROOKLYN 012 C020002 NY 012 C030002 11219 012 A000003 DEUTSCHE BANK TRUST COMPANY AMERICAS (PREF.) 012 B000003 85-05212 012 C010003 NEW YORK 012 C020003 NY 012 C030003 10005 013 A000001 ERNST & YOUNG, LLP 013 B010001 BOSTON 013 B020001 MA 013 B030001 02116 PAGE 3 013 B040001 5072 015 A000001 BROWN BROTHERS HARRIMAN & CO. 015 B000001 C 015 C010001 BOSTON 015 C020001 MA 015 C030001 02109 015 E010001 X 018 000000 Y 019 A000000 Y 019 B000000 56 019 C000000 PIONEERFDS 020 A000001 SANFORD C. BERNSTEIN & CO., INC. 020 B000001 13-4132953 020 C000001 2 020 A000002 UBS SECURITIES 020 B000002 13-2638166 020 C000002 0 020 A000003 MERRILL LYNCH, PIERCE, FENNER & SMITH 020 B000003 13-5674085 020 C000003 0 020 A000004 WELLS FARGO SECURUTIES LLC 020 B000004 94-3379992 020 C000004 0 020 C000005 0 020 C000006 0 020 C000007 0 020 C000008 0 020 C000009 0 020 C000010 0 021 000000 3 022 A000001 JP MORGAN SECURITIES, LLC 022 B000001 13-3379014 022 C000001 8415 022 D000001 0 022 A000002 CITIGROUP GLOBAL MARKETS, INC. 022 B000002 11-2418191 022 C000002 7425 022 D000002 0 022 A000003 MORGAN KEEGAN & CO., INC. 022 B000003 64-0474907 022 C000003 4727 022 D000003 0 022 A000004 BNY MELLON CAPITAL MARKETS, LLC 022 B000004 23-2384977 022 C000004 4482 022 D000004 0 022 A000005 SOCIETE GENERALE 022 B000005 00-0000000 022 C000005 537 022 D000005 3061 022 A000006 BLACKROCK INVESTMENTS, LLC PAGE 4 022 B000006 00-0000000 022 C000006 0 022 D000006 3400 022 A000007 OPPENHEIMER & CO., INC. 022 B000007 13-5657518 022 C000007 2793 022 D000007 0 022 A000008 MESIROW FINANCIAL, INC. 022 B000008 00-0000000 022 C000008 0 022 D000008 2024 022 A000009 MERRILL LYNCH, PIERCE, FENNER & SMITH 022 B000009 13-5674085 022 C000009 0 022 D000009 1990 022 A000010 BARCLAYS CAPITAL, INC. 022 B000010 61-0316560 022 C000010 0 022 D000010 559 023 C000000 28379 023 D000000 11034 024 000000 N 025 D000001 0 025 D000002 0 025 D000003 0 025 D000004 0 025 D000005 0 025 D000006 0 025 D000007 0 025 D000008 0 026 A000000 N 026 B000000 Y 026 C000000 N 026 D000000 Y 026 E000000 N 026 F000000 N 026 G010000 N 026 G020000 N 026 H000000 N 027 000000 N 028 A010000 0 028 A020000 0 028 A030000 0 028 A040000 0 028 B010000 0 028 B020000 0 028 B030000 0 028 B040000 0 028 C010000 0 028 C020000 0 028 C030000 0 PAGE 5 028 C040000 0 028 D010000 0 028 D020000 0 028 D030000 0 028 D040000 0 028 E010000 0 028 E020000 0 028 E030000 0 028 E040000 0 028 F010000 0 028 F020000 0 028 F030000 0 028 F040000 0 028 G010000 0 028 G020000 0 028 G030000 0 028 G040000 0 028 H000000 0 030 A000000 0 030 B000000 0.00 030 C000000 0.00 031 A000000 0 031 B000000 0 032 000000 0 033 000000 0 035 000000 0 036 B000000 0 038 000000 0 042 A000000 0 042 B000000 0 042 C000000 0 042 D000000 0 042 E000000 0 042 F000000 0 042 G000000 0 042 H000000 0 043 000000 0 044 000000 0 045 000000 Y 046 000000 N 047 000000 Y 048 000000 0.600 048 A010000 0 048 A020000 0.000 048 B010000 0 048 B020000 0.000 048 C010000 0 048 C020000 0.000 048 D010000 0 048 D020000 0.000 048 E010000 0 PAGE 6 048 E020000 0.000 048 F010000 0 048 F020000 0.000 048 G010000 0 048 G020000 0.000 048 H010000 0 048 H020000 0.000 048 I010000 0 048 I020000 0.000 048 J010000 0 048 J020000 0.000 048 K010000 0 048 K020000 0.000 049 000000 N 050 000000 N 051 000000 N 052 000000 N 053 A000000 N 054 A000000 Y 054 B000000 Y 054 C000000 Y 054 D000000 N 054 E000000 N 054 F000000 N 054 G000000 N 054 H000000 Y 054 I000000 N 054 J000000 Y 054 K000000 N 054 L000000 N 054 M000000 Y 054 N000000 N 054 O000000 N 055 A000000 N 055 B000000 N 056 000000 N 057 000000 N 058 A000000 N 059 000000 Y 060 A000000 Y 060 B000000 Y 061 000000 0 062 A000000 Y 062 B000000 0.0 062 C000000 0.0 062 D000000 0.0 062 E000000 0.0 062 F000000 0.0 062 G000000 0.0 062 H000000 0.0 062 I000000 0.0 PAGE 7 062 J000000 0.0 062 K000000 0.0 062 L000000 0.0 062 M000000 0.0 062 N000000 0.0 062 O000000 141.8 062 P000000 0.0 062 Q000000 0.8 062 R000000 0.0 063 A000000 0 063 B000000 23.0 064 A000000 Y 064 B000000 Y 065 000000 N 066 A000000 N 067 000000 N 068 A000000 N 068 B000000 N 069 000000 N 070 A010000 Y 070 A020000 Y 070 B010000 N 070 B020000 N 070 C010000 Y 070 C020000 N 070 D010000 N 070 D020000 N 070 E010000 Y 070 E020000 N 070 F010000 N 070 F020000 N 070 G010000 Y 070 G020000 N 070 H010000 N 070 H020000 N 070 I010000 N 070 I020000 N 070 J010000 Y 070 J020000 Y 070 K010000 Y 070 K020000 Y 070 L010000 N 070 L020000 N 070 M010000 N 070 M020000 N 070 N010000 N 070 N020000 N 070 O010000 Y 070 O020000 N 070 P010000 Y 070 P020000 N PAGE 8 070 Q010000 N 070 Q020000 N 070 R010000 N 070 R020000 N 071 A000000 28076 071 B000000 12281 071 C000000 450187 071 D000000 3 072 A000000 6 072 B000000 14418 072 C000000 0 072 D000000 0 072 E000000 0 072 F000000 1382 072 G000000 100 072 H000000 0 072 I000000 9 072 J000000 4 072 K000000 0 072 L000000 14 072 M000000 8 072 N000000 12 072 O000000 0 072 P000000 0 072 Q000000 0 072 R000000 31 072 S000000 137 072 T000000 0 072 U000000 0 072 V000000 0 072 W000000 249 072 X000000 1946 072 Y000000 0 072 Z000000 12471 072AA000000 1136 072BB000000 0 072CC010000 16555 072CC020000 0 072DD010000 13286 072DD020000 0 072EE000000 0 073 A010000 0.5700 073 A020000 0.0000 073 B000000 0.0000 073 C000000 0.0000 074 A000000 2243 074 B000000 0 074 C000000 0 074 D000000 449717 074 E000000 0 074 F000000 0 PAGE 9 074 G000000 0 074 H000000 0 074 I000000 2600 074 J000000 4126 074 K000000 0 074 L000000 8811 074 M000000 205 074 N000000 467702 074 O000000 0 074 P000000 221 074 Q000000 0 074 R010000 0 074 R020000 0 074 R030000 0 074 R040000 271 074 S000000 150008 074 T000000 317202 074 U010000 23346 074 U020000 0 074 V010000 13.59 074 V020000 0.00 074 W000000 0.0000 074 X000000 9688 074 Y000000 0 075 A000000 0 075 B000000 0 076 000000 15.99 077 A000000 N 078 000000 N 080 C000000 0 081 B000000 0 082 B000000 0 083 B000000 0 084 B000000 0 086 A010000 149 086 A020000 1961 086 B010000 0 086 B020000 0 086 C010000 0 086 C020000 0 086 D010000 0 086 D020000 0 086 E010000 0 086 E020000 0 086 F010000 0 086 F020000 0 087 A010000 COMMON STOCK 087 A020000 723762100 087 A030000 MAV 087 B010000 PREFERRED STOCK - SERIES A 087 B020000 723762209 PAGE 10 087 C010000 PREFERRED STOCK - SERIES B 087 C020000 723762308 088 A000000 N 088 B000000 N 088 C000000 N 088 D000000 Y SIGNATURE MARK E. BRADLEY TITLE TREASURER